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NCT Number: NCT06489587

Creatine Supplementation At Simulated Altitude

Creatine supplementation has been shown to increase exercise performance at sea level. The goal of this study is to determine the effects of creatine supplementation on exercise performance at simulated altitude.

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Key information

Conditions

Exercise Performance

Age range

18 year–40 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

About this study

Military personnel often encounter harsh environments such as high altitudes and hypoxic conditions, leading to significant constraints on their exercise capacity and performance. At sea-level creatine supplementation increases exercise performance; however no experimental studies have examined the effect of creatine supplementation at simulated altitude. The overall objective of this study is to investigate the effects of creatine supplementation on exercise performance, via a repeated sprints test (Wingate Test) after a 2-day supplementation period, compared to a placebo group.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 18-40 years old
  • BMI 18.5 to 40 kg/m2
  • Habitually active (>150 minutes per week of moderate-vigorous physical activity)

Exclusion criteria

  • Pregnant or trying to become pregnant
  • Recent use of creatine supplementation
  • Supplemental allergies

Treatment and study plan

Placebo

Dietary Supplement

Participants given 40 grams of glucose in total to be taken over 2 days, in 5-gram servings (4 capsules), 4 times per day.

Creatine

Dietary Supplement

Participants given 40 grams of creatine in total to be taken over 2 days, in 5-gram servings (4 capsules), 4 times per day.

Primary outcomes

  1. Peak power

    Time frame: Change from baseline to 3 days

    Peak power is measured in watts.

Secondary outcomes

  1. Body Weight

    Time frame: Change from baseline to 3 days

    Body weight is measured in kilograms.

  2. Relative peak power

    Time frame: Change from baseline to 3 days

    Relative peak power is measured in watts per kilogram.

  3. Mean power

    Time frame: Change from baseline to 3 days

    Mean power is measured in watts.

  4. Relative mean power

    Time frame: Change from baseline to 3 days

    Relative mean power is measured in watts per kilogram.

  5. Fatigue index

    Time frame: Change from baseline to 3 days

    Fatigue index is measured in watts per second.

Study contacts

Contact information is provided by the study sponsor or research team.

Todd Hagobian, PhD

CONTACT

[email protected]

8057567511

Sponsors and collaborators

Lead sponsor

California Polytechnic State University-San Luis Obispo

Other

Registry information

Important dates

Study start
2024
Primary completion
2025
Study completion
2026
First posted
Jul 8, 2024
Registry last updated
Jul 8, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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