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Completed

NCT Number: NCT05771246

Craniofacial Morphology And Sella Turcica Bridging Associated With Third Molar Agenesis.

The aim of this retrospective study is to analyze the third molar agenesis with respect to sella turcica bridging and other craniofacial patterns in patients asking for orthodontic consultation. The main question[s] it aims to answer are:

* is there a relationship between third molar agenesis and sella turchina bridging? * is there a relationship between third molar agenesis and craniofacial patterns?

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Key information

Conditions

Tooth Agenesis Anodontia Congenital Abnormalities Congenital, Hereditary, and Neonatal Diseases and Abnormalities Stomatognathic Diseases Stomatognathic System Abnormalities Tooth Abnormalities Tooth Diseases

Age range

8 year–18 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Unit of Orthodontics and Pediatric Dentistry - Section of Dentistry - Department of Clinical, Surgical, Diagnostic and Pediatrics - University of Pavia

Pavia, Lombardy, 27100, Italy

About this study

Patients referring for orthodontic consultation at the Unit of Orthodontics and Pediatric Dentistry, Section of Dentistry, Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, 27100 Pavia, Italy, will be enrolled for the study according to the inclusion criteria. For each patient, lateral cephalometric radiograph and panoramic radiograph will be performed. For each lateral cephalometric radiograph, a cephalometric tracing will be performed with DeltaDent software (version 2.5.12, Outside Format, Pandino, Italy). Riedel's ANB angle [Riedel 1952] has been chosen to determine patients' skeletal class. Steiner's SN^GoGn angle [Steiner 1953] has been chosen to evaluate skeletal divergence. Facial axis (BaNa^CCGn), Lower Facial Height (LFH) and mandibular plan angle (FH^GoMe) from Rickett's analysis [Rickett's 1961] have been adopted to determine facial growth. According to Jaraback's cephalometric analysis [Jaraback 1985], saddle angle, articular angle, upper gonial angle, lower gonial angle will be measured to assess the growth pattern. Linear measurements of sella depth, sella diameter and interclinoid distance [Silverman 1957; Kisling 1966] will be calculated. Linear regressions between craniofacial patterns, sella turcica bridging and third molar agenesis will be calculated. A control group with no third molar agenesis will be provided.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • G stage of Demirjian's classification for third molar maturation or absence of third molar germs
  • Patients with one lateral cephalometric digital radiograph executed in Natural Head Position (patients were asked to keep the teeth in contact and the lips relaxed).
  • Patients with panoramic radiograph;

Exclusion criteria

  • Ascertained previous surgical extraction/s of third molar/s
  • Orthopedic/orthodontic therapy
  • Orthognathic surgery.

Treatment and study plan

Radiographic evaluation

Diagnostic Test

Panoramic and lateral cephalometric radiographs with cephalometric analysis will be performed.

Primary outcomes

  1. Linear regression between third molar agenesis and ANB

    Time frame: Baseline

    ANB is calculated according to Riedel's analysis: angle formed between Point A (maxillary sovraspinal point), point B (Bubmental mandibular point) and N (Nasion)

  2. Linear regression between third molar agenesis and Interclinoid Distance

    Time frame: Baseline

    Distance between tuberculum sella (TS) and dorsum sella (DS).

  3. Linear regression between third molar agenesis and Sella Depth.

    Time frame: Baseline

    Distance of a line dropped perpendicular from the interclinoid distance to the deepest point of the sella floor.

  4. Linear regression between third molar agenesis and Sella Diameter

    Time frame: Baseline

    Distance between tuberculum sella and the farthest point on the inner wall of the sella.

  5. Linear regression between third molar agenesis and Sn^GoGn.

    Time frame: Baseline

    Steiner's Sn^GoGn is the angle formed between 2 planes: cranial base line (SN) and mandibular plane (GoGn)

  6. Linear regression between third molar agenesis and ArGo^GoGn

    Time frame: Baseline

    Jaraback's Ar^Go^Gn is the angle formed between the 2 planes: ArGo and GoGn

Sponsors and collaborators

Lead sponsor

University of Pavia

Other

Registry information

Official study title

Third Molar Agenesis Related To Craniofacial Pattern And Sella Turcica Bridging: A Retrospective Cephalometric Study

Important dates

Study start
2023
Primary completion
2023
Study completion
2023
First posted
Mar 16, 2023
Registry last updated
Jul 9, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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