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Completed

NCT Number: NCT06304038

Cost-consequence Analysis of Influenza Vaccination in a Teaching Hospital in Rome

Flu vaccination, as well as being effective to prevent seasonal influenza, decreases staff illness and absenteeism and reduces costs resulting from loss of productivity. Despite the effectiveness of flu vaccination, the seasonal coverage among healthcare workers is usually low. The aim of this retrospective observational study is to analyze the vaccination coverage rate among all employees (healthcare workers and administrative staff) of a large teaching hospital in Rome during the 2017-2018 influenza season, to perform a cost-consequence analysis of influenza vaccination (by evaluating the absenteeism due to illness in the epidemic period), and to assess the impact of vaccination in terms of both costs and sick days.

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Key information

Conditions

Influenza Vaccine Cost-Benefit Analysis Infections Influenza, Human Orthomyxoviridae Infections RNA Virus Infections Respiratory Tract Diseases Respiratory Tract Infections Virus Diseases

Sex eligibility

All sexes

Study type

Observational

Primary location

Fondazione Policlinico Universitario "A.Gemelli" IRCCS

Rome, 00168, Italy

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthcare workers at Fondazione Policlinico Universitario "A.Gemelli" IRCCS

Exclusion criteria

  • Healthcare workers not working at Fondazione Policlinico Universitario "A.Gemelli" IRCCS

Treatment and study plan

Flu Vaccine

Drug

Administration of quadrivalent split inactivated non-adjuvanted flu vaccine Fluarix Tetra

Primary outcomes

  1. Effectiveness of the quadrivalent vaccine

    Time frame: 33 weeks

    Effectiveness of the quadrivalent vaccine in reducing the number of working days lost due to influenza syndrome

  2. Economic impact of the quadrivalent vaccine

    Time frame: 33 weeks

    Economic impact (for the company and society) of vaccination as part of a vaccination campaign on the healthcare workers of the teaching hospital.

Secondary outcomes

  1. Expected economic savings for each one percentage point increase in vaccination coverage

    Time frame: 33 weeks

    Expected economic savings for each one percentage point increase in coverage on the health personnel of the teaching hospital

  2. Non-economic incentives for healthcare personnel who decide to vaccinate

    Time frame: 33 weeks

    Non-economic incentives for healthcare personnel who decide to vaccinate, in view of the financial savings for the company, linked to increased vaccination coverage

Sponsors and collaborators

Lead sponsor

Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Other

Registry information

Official study title

Cost-consequence Analysis of Influenza Vaccination Among the Staff of a Large Teaching Hospital in Rome, Italy: A Pilot Study

Important dates

Study start
2017
Primary completion
2018
Study completion
2019
First posted
Mar 12, 2024
Registry last updated
Mar 12, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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