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Completed

NCT Number: NCT04555018

Correlation Between Dehydroepiandrosterone Sulfate and Sebum Level in Adult Female Acne Vulgaris

The aim of this study is to determine the correlation between Dehydroepiandrosterone sulfate (DHEAS) and sebum level in adult female acne. A cross sectional study was conducted with 50 samples, in June to October 2017.

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Key information

Conditions

Acne Vulgaris Acneiform Eruptions Female Sebaceous Gland Diseases Skin Diseases Skin and Connective Tissue Diseases

Age range

25 year–49 year

Sex eligibility

Female

Study type

Observational

Primary location

Indonesia dr. Cipto Mangunkusumo Hospital

Jakarta, Jakarta Pusat, 10430, Indonesia

About this study

Epidemiological studies have shown that number of adult female acne vulgaris (AV) increases. Hormone, sebum production, Propionibacterium acne and inflammatory process are factors involved in AV development. The aim of this study is to determine the correlation between Dehydroepiandrosterone sulfate (DHEAS) and sebum level in adult female acne. This research used cross sectional study with 50 samples, aged 25-49 years by consecutive sampling. The degree of acne vulgaris was evaluated using Lehman criteria , and then the sebum level and DHEAS were measured objectively using sebumeter and serum, respectively.

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Female, age 25-29 years
  • Diagnosed with mild to severe acne vulgaris
  • Agree to participate

Exclusion criteria

  • History of taking antiandrogen drugs
  • History of taking oral and topical antibiotics, using topical retinoid and BPO in the last 4 weeks
  • History of taking oral isotretinoin in the last 6 months
  • Pregnancy or breastfeeding

Treatment and study plan

Primary outcomes

  1. Sebum level

    Time frame: One day

    Using sebumeter to evaluate the sebum level objectively

  2. Dehydroepiandrosterone sulfate

    Time frame: One day

    Blood serum was used to evaluate Dehydroepiandrosterone sulfate level.

Sponsors and collaborators

Lead sponsor

Dr.dr.Irma Bernadette, SpKK (K)

Other

Registry information

Important dates

Study start
2017
Primary completion
2017
Study completion
2017
First posted
Sep 18, 2020
Registry last updated
Sep 18, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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