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OpenTrials
Completed

NCT Number: NCT05898607

Continuous Ultrasound Guided Erector Spinae Plane Block vs Thoracic Paravertebral Block

in this study the investigators will investigate and compare the analgesic efficacy of two techniques (continuous TPVB and continuous ESPB) in relieving thoracotomy pain

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Key information

Age range

21 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Menoufia university

Cairo, Shibin Elkom, Egypt

About this study

General Anesthesia will be induced with Fentanyl (1-2 μg/kg), Propofol (2-3 mg/kg), and Atracurium (0.5-0.8 mg/kg). Pressure controlled Volume guarantee Ventilation mode will be used to maintain O2 Saturation Above 98% and End tidal co2 Around 30-35 mmHg. Anesthesia will be maintained with Isoflurane 1.2 Minimum Alveolar Concentration inhalation after induction Group A: Patients will receive Loading dose of 20 ml 0.25% bupivacaine then continuous infusion U/S-Guided TPVB of 5 ml/h of 0.125% bupivacaine started through the catheter before the surgical procedure intraoperative and Group B: Patients will receive Loading dose of 20 ml 0.25% bupivacaine then continuous U/S-Guided ESPB of 5 ml/h of 0.125% bupivacaine started through the catheter before the surgical procedure intraoperative.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Eligible 40 patients will be older than 21 years old with American society of anesthesia physical status I& II scheduled for elective thoracotomy

Exclusion criteria

  • Patients who are:
  • Uncooperative.
  • Having allergy to any of the study drugs.
  • Known abuse of alcohol or medication.
  • Having Local infection at the site of injection or systemic infection.
  • Pregnancy.
  • With coagulation disorders or on anticoagulation therapy

Treatment and study plan

continuous Thoracic paravertebral block

Other

continuous infusion U/S-Guided TPVB of 5 ml/hr of 0.125% bupivacaine started through the catheter before the surgical procedure intraoperative.

Other names: TPVB

continuous Erector spinae plane block

Other

continuous U/S-Guided ESPB of 5 ml/hr of 0.125% bupivacaine started through the catheter before the surgical procedure

Other names: ESPB

Primary outcomes

  1. Compare the VAS score postoperative of (U/S)-guided continuous (ESPB) to continuous (TPVB) following thoracotomy

    Time frame: 48 hours

    visual analogue scale (VAS) Score

Secondary outcomes

  1. 1 st call analgesia

    Time frame: 1 hour

    mg

  2. Total rescue opioid dose used

    Time frame: 48 hour

    mg

  3. patient satisfaction at 24 hours

    Time frame: 24 hours

  4. occurrence of adverse events

    Time frame: 24hours

  5. hospital stay

    Time frame: 1 week

    days

Sponsors and collaborators

Lead sponsor

Amal Gouda Elsayed Safan

Other

Collaborators

  • Mohamed Emad Basune
  • Rabab Mohammed Habeeb
  • Wesam Eldin Sultan

Registry information

Official study title

Continuous Ultrasound Guided Erector Spinae Plane Block vs Thoracic Paravertebral Block for Postoperative Analgesia in Patients Undergoing Thoractomy

Important dates

Study start
2023
Primary completion
2023
Study completion
2024
First posted
Jun 12, 2023
Registry last updated
Jan 26, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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