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Recruiting

NCT Number: NCT04687865

Constitution of a Biobank for Studies Related to Organ Transplantation (Lyon Centaure Biocollection)

This study aims to constitute a collection of biological materials from in transplant patients and to provide biological materials from transplanted patients in order :

i) validate new theory on the cause of allograft loss, ii) develop innovative biomarker for rejection and other transplantation-related conditions (such as BK virus nephropathy, Post-transplant lymphoproliferative disorder ( PTLD) ...)

Recruiting

Interested in participating?

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Key information

Conditions

Organ Transplantation

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Male or Female patient ≥18 years old
  • Recipient of an organ transplant
  • Written informed consent

Exclusion criteria

  • Non-affiliation to a social security system.
  • Subjects deprived of liberties
  • Pregnant or breastfeeding woman

Treatment and study plan

biobank

Other

For each patient included in the study the following samples will be collected at the indicated time points after transplantation:

  • Serum samples and plasma sample: Day1, Month 1, Month 3, Month 6, Month 12, month 60, month 120 and at the time of each allograft biopsy.
  • Urines samples: Month 3 and Month 12 and at the time of each allograft biopsy.
  • Peripheral Blood Mononuclear Cell (PBMC): for each organ allograft biopsy.
  • Allograft biopsies: systematically at Month 3, and Month 12, and for cause in case of allograft dysfunction.

Primary outcomes

  1. the biological samples

    Time frame: At inclusion

    The goal of this study is to provide biological materials from transplanted patients

  2. Change Biological Samples

    Time frame: Month 1

    The goal of this study is to provide biological materials from transplanted patients

  3. Change Biological Samples

    Time frame: Month 3

    The goal of this study is to provide biological materials from transplanted patients

  4. Change Biological Samples

    Time frame: Month 6

    The goal of this study is to provide biological materials from transplanted patients

  5. Change Biological Samples

    Time frame: Month 12

    The goal of this study is to provide biological materials from transplanted patients

  6. Change Biological Samples

    Time frame: Month 60

    The goal of this study is to provide biological materials from transplanted patients

  7. Change Biological Samples

    Time frame: Month 120

    The goal of this study is to provide biological materials from transplanted patients

Study contacts

Contact information is provided by the study sponsor or research team.

Emmanuel Morelon, MD

CONTACT

[email protected]

04 72 11 01 70 ext. +33

Olivier Thaunat, MD

CONTACT

[email protected]

04 72 11 69 28 ext. +33

Sponsors and collaborators

Lead sponsor

Hospices Civils de Lyon

Other

Registry information

Official study title

Biological Material Bank for Studies Related to Organ Transplantation

Important dates

Study start
2020
Primary completion
2040
Study completion
2040
First posted
Dec 29, 2020
Registry last updated
Mar 7, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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