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Completed

NCT Number: NCT02474628

Consistencies in Responses to Sodium Bicarbonate?

Intervention studies do not account for high within-individual variation potentially compromising the magnitude of an effect. Repeat administration of a treatment allows quantification of individual responses and determination of the consistency of responses. The investigators aim to determine the consistency of metabolic and exercise responses following repeated administration of sodium bicarbonate (SB). Design and Methods: 15 physically active males will complete six cycling capacity tests at 110% of maximum power output (CCT110%) following ingestion of either 0.3 g∙kg-1Body Mass of SB (4 trials) or placebo (PL, 2 trials). Blood pH, bicarbonate, base excess and lactate will be determined at baseline, pre-exercise, post-exercise and 5-min post-exercise. Total work done (TWD) will be recorded as the exercise outcome.

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Key information

Conditions

Sports Nutritional Physiological Phenomena

Age range

18 year–40 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

University of Sao Paulo

São Paulo, 05508-30, Brazil

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • recreationally active males

Exclusion criteria

  • use of dietary supplements in the past 6 months
  • the presence of any musculoskeletal disorder
  • the use of anabolic steroids

Treatment and study plan

Sodium bicarbonate

Dietary Supplement

Calcium Carbonate

Dietary Supplement

Primary outcomes

  1. blood pH

    Time frame: 5 min after a physical exercise test

Secondary outcomes

  1. blood bicarbonate

    Time frame: 5 min after a physical exercise test

  2. blood lactate

    Time frame: 5 min after a physical exercise test

  3. anaerobic exercise capacity

    Time frame: 4 hours after supplementation

    as assessed by cycling capacity tests at 110% of maximum power output

Sponsors and collaborators

Lead sponsor

University of Sao Paulo

Other

Registry information

Official study title

Consistencies in Responses to Sodium Bicarbonate Supplementation: a Randomised, Repeated Measures, Counterbalanced and Double-blind Study

Important dates

Study start
2013
Primary completion
2014
Study completion
2014
First posted
Jun 18, 2015
Registry last updated
Jun 18, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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