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NCT Number: NCT07517614

Condylar Offset and Outcomes in Primary Total Knee Arthroplasty

This prospective cohort study aims to evaluate the effect of posterior condylar offset (PCO) and anterior condylar offset (ACO) changes on functional outcomes after primary total knee arthroplasty (TKA). Standardized imaging and clinical assessment protocols will be used to determine optimal PCO and ACO ranges associated with improved postoperative range of motion, patient-reported outcomes, and reduced anterior knee symptoms.

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Key information

Conditions

Knee Arthritis Osteoarthritis

Age range

50 year–85 year

Sex eligibility

All sexes

Study type

Observational

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • diagnosis of primary knee osteoarthiritis
  • indication of knee arthroplasty
  • 50-85 years
  • ability t oprovide informed consent and comply with follow up

Exclusion criteria

  • revision knee arthroplasty
  • inflammatory arthritis
  • severe corona deformity (>20 varus/valgus)
  • previous knee surgery or fracture

Treatment and study plan

Primary outcomes

  1. Maximum Knee Flexion

    Time frame: 12 months postoperatively

    maximum active knee flexion measured in degrees using a goniometer during clinical examination

Secondary outcomes

  1. Knee Society Score

    Time frame: 3,6,12 months postoperatively

    The Knee Society Score (KSS) is a clinician-reported outcome measure consisting of two components: the Knee Score (pain, stability, and range of motion) and the Function Score (walking distance and stair climbing). Each component ranges from 0 to 100, with a total possible score of 200. Higher scores indicate better knee function and clinical outcomes.

  2. WOMAC score

    Time frame: 3,6,12 months postoperatively

    The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) is a patient-reported outcome measure assessing pain, stiffness, and physical function. The total score ranges from 0 to 96, with higher scores indicating worse pain, stiffness, and functional limitation.

  3. Change in Anterior and Posterior Condylar Offset

    Time frame: preoperative graphy and postoperative 1st day graphy

    difference between preoperative and postoperative 1st day anterior condylar offset mesaured on lateral knee radiographs

Sponsors and collaborators

Lead sponsor

SB Istanbul Education and Research Hospital

Other

Registry information

Official study title

Prospective Evaluation of Posterior and Anterior Condylar Offset and Their Impact on Functional Outcomes in Primary Total Knee Arthroplasty

Acronym: OFFSET-TKA

Important dates

Study start
2026
Primary completion
2026
Study completion
2027
First posted
Apr 8, 2026
Registry last updated
Apr 8, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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