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OpenTrials
Completed

NCT Number: NCT05006898

Compound to Control Presbyopia Symptoms

Low dose compose to control presbyopia symptoms

Completed

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Key information

Conditions

Presbyopia Eye Diseases Refractive Errors

Age range

40 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 1

Primary location

Optall Vision

Mexico City, 01090, Mexico

About this study

A los dose compound including pilocarpine, brimonidine and oxymetazoline was use to control presbyopia symptoms compared to pilocarpine and brimonidine in low doses.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • healthy
  • Presbyopic
  • 40 - 59 years

Exclusion criteria

  • Diabetics
  • Previous eye surgery
  • Previous eye disease
  • > 0.50 myopia
  • > 1.5 hyperopia or astigmatism

Treatment and study plan

PBO to control presbyopia symptoms

Combination Product

Low dose PBO to control presbyopia symptoms

Other names: Pilocarpine, Brimonidine, Oxymetazoline

Primary outcomes

  1. Jaeger notation near uncorrected visual acuity change

    Time frame: 1 hour

    Number of lines improved 1 hour after drug instillation

  2. Comparison of PBO compound Jaeger notation improvement vs Pilocarpine or Brimonidine alone

    Time frame: 1 hour

    Number of lines improve comparing PBO compound vs Pilocarpine or Brimonidine

Sponsors and collaborators

Lead sponsor

Optall Vision

Other

Registry information

Official study title

Synergistic Use of Pilocarpine-Brimonidine-Oxymetazoline to Control Presbyopia Symptoms

Important dates

Study start
2020
Primary completion
2020
Study completion
2020
First posted
Aug 16, 2021
Registry last updated
Aug 19, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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