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NCT Number: NCT07358416

Complications and Antiplatelet and Anticoagulant Therapy in Vascular Surgery.

The goal of this retrospective clinical trial is to find out association antiplatelet and anticoagulant therapy with perioperative complications in non-cardiac vascular surgery in patients . The main questions it aims to answer are:

Does the use of antiplatelet agents and anticoagulants affect the development of complications in the perioperative period during operations on the main arteries? Does discontinuing antiplatelet and anticoagulant medications affect the development of perioperative complications in major artery surgeries?? Researchers will compare with patients who didn't use antiplatelets and anticoagulant drugs to see ift he incidence of complications comparable?

This is a retrospective study based on the analysis of medical records (case histories).

Active, Not Recruiting

This study is active but is not currently recruiting participants.

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Key information

Conditions

Thrombosis Bleeding Cardiovascular Diseases Cerebral Hypoxia During and/or Resulting From A Procedure Embolism and Thrombosis Hemorrhage Pathologic Processes Pathological Conditions, Signs and Symptoms Vascular Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

NRCS Petrovsky

Moscow, 119991, Russia

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients who received surgical treatment on the main arteries.

Exclusion criteria

  • Patients who received surgical treatment on the main veins.

Treatment and study plan

Aspirin

Drug

Patients who take aspirin until the operation day

clopidogrel

Drug

Patients who take clopidogrel until the operation day

Ticagrelor

Drug

Patients who take ticagrelor until the operation day

dabigatran

Drug

Patients who take dabigatran until the operation day

Rivaroxaban

Drug

Patients who take rivaroxaban until the operation day

Apixaban

Drug

Patients who take apixaban until the operation day

Warfarin

Drug

Patients who take warfarin until the operation day

Aspirin + clopidogrel

Drug

Patients who take aspirin and clopidogrel until the operation day

Aspirin + Ticagrelor

Drug

Patients who take aspirin and ticagrelor until the operation day

Aspirin + Apixaban

Drug

Patients who take aspirin and apixaban until the operation day

Aspirin + rivaroxaban

Drug

Patients who take aspirin and rivaroxaban until the operation day

Clopidogrel + Apixaban

Drug

Patients who take clopidogrel and apixaban until the operation day

Clopidogrel + Rivaroxaban

Drug

Patients who take clopidogrel and rivaroxaban until the operation day

Primary outcomes

  1. Bleeding

    Time frame: First 24 hours after operation

    Case of bleeding or haematoma development

Secondary outcomes

  1. Trombosis

    Time frame: First 24 hours after operation

Sponsors and collaborators

Lead sponsor

Petrovsky National Research Centre of Surgery

Other

Registry information

Official study title

Determination the Safety of Disaggregant and Anticoagulant Therapy in the Development of Complications in Noncardiac Vascular Surgery.

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Jan 22, 2026
Registry last updated
Jan 22, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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