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NCT Number: NCT07481045

Compensatory Inferior Turbinate Surgery in Septorhinoplasty

Nasal obstruction is a common complaint among patients undergoing septorhinoplasty. In addition to septal deviation, compensatory inferior turbinate hypertrophy may contribute to impaired nasal airflow. For this reason, some surgeons routinely perform inferior turbinate reduction during septorhinoplasty. However, the necessity and functional benefit of this additional procedure remain controversial.

The aim of this randomized controlled study is to evaluate whether compensatory inferior turbinate surgery provides additional functional benefit when performed simultaneously with septorhinoplasty. Patients undergoing septorhinoplasty will be randomly assigned to either septorhinoplasty alone or septorhinoplasty combined with inferior turbinate surgery.

Functional outcomes will be assessed using both subjective and objective measures. Subjective nasal obstruction will be evaluated using the Nasal Obstruction Symptom Evaluation (NOSE) scale, and objective nasal airflow will be assessed using peak nasal inspiratory flow (PNIF). Patients will be followed for six months after surgery.

The results of this study are expected to clarify the role of compensatory inferior turbinate surgery in patients undergoing septorhinoplasty and provide evidence regarding whether routine turbinate intervention is necessary in this patient population.

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Key information

Age range

18 year–53 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Etlik City Hospital

Ankara, 06010, Turkey (Türkiye)

About this study

Nasal obstruction is a common complaint among patients with nasal septal deviation and is one of the major indications for septorhinoplasty. Although correction of septal deviation often improves nasal airflow, some patients present with compensatory inferior turbinate hypertrophy that may contribute to persistent nasal obstruction. For this reason, inferior turbinate surgery is frequently performed during septorhinoplasty. However, the additional functional benefit of routine turbinate intervention in these patients remains controversial.

This prospective randomized controlled study aims to evaluate the effect of compensatory inferior turbinate surgery on functional outcomes in patients undergoing septorhinoplasty. Patients with nasal obstruction due to septal deviation who are scheduled for septorhinoplasty will be enrolled and randomly assigned to one of two treatment groups: septorhinoplasty alone or septorhinoplasty combined with inferior turbinate surgery.

All surgical procedures will be performed using standard septorhinoplasty techniques. In the intervention group, inferior turbinate reduction will be performed during the same surgical session. Postoperative functional outcomes will be evaluated using both subjective and objective assessment tools. Subjective nasal obstruction will be assessed with the Nasal Obstruction Symptom Evaluation (NOSE) scale, and objective nasal airflow will be measured using peak nasal inspiratory flow (PNIF).

Patients will be followed for six months after surgery. Functional outcomes will be compared between the two groups to determine whether additional inferior turbinate surgery provides clinically meaningful improvement in nasal airway function when performed simultaneously with septorhinoplasty.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients older than 18 years
  • Patients presenting with nasal obstruction and aesthetic concerns requiring septorhinoplasty
  • Presence of nasal septal deviation confirmed by anterior rhinoscopy, nasal endoscopy, or computed tomography
  • Presence of compensatory inferior turbinate hypertrophy in the contralateral nasal cavity
  • Patients willing to participate and able to provide informed consent

Exclusion criteria

  • Previous nasal, septal, or turbinate surgery
  • Chronic rhinosinusitis with or without nasal polyps
  • Bilateral inferior turbinate hypertrophy
  • Absence of compensatory inferior turbinate hypertrophy
  • Patients requiring additional nasal procedures or grafting techniques beyond the standardized surgical protocol
  • Incomplete follow-up

Treatment and study plan

septorhinoplasty

Procedure

Standard open functional septorhinoplasty was performed under general anesthesia, including septoplasty, dorsal profile alignment with transverse and lateral osteotomies, tipplasty, bilateral spreader graft placement, and columellar strut grafting. Silicone nasal splints were placed bilaterally and removed after 72 hours.

Inferior turbinate surgery

Procedure

Inferior turbinate reduction was performed on the non-deviated side using submucosal radiofrequency ablation followed by turbinate lateralization to improve nasal airway patency.

Primary outcomes

  1. Change in Nasal Obstruction Symptom Evaluation (NOSE) score

    Time frame: Preoperative baseline and 6 months after surgery

    The Nasal Obstruction Symptom Evaluation (NOSE) scale is a validated patient-reported questionnaire used to assess the severity of nasal obstruction. Scores range from 0 to 100, with higher scores indicating more severe nasal obstruction.

Secondary outcomes

  1. Change in Peak Nasal Inspiratory Flow (PNIF)

    Time frame: Preoperative baseline and 6 months after surgery

    Peak Nasal Inspiratory Flow (PNIF) is an objective measure of nasal airflow.

Sponsors and collaborators

Lead sponsor

Saglik Bilimleri Universitesi

Other

Registry information

Official study title

Effect of Concomitant Compensatory Inferior Turbinate Surgery on Functional Outcomes After Septorhinoplasty: A Randomized Controlled Trial

Acronym: CIT

Important dates

Study start
2023
Primary completion
2025
Study completion
2025
First posted
Mar 18, 2026
Registry last updated
Mar 18, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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