Skip to main content
OpenTrials
Not Yet Recruiting

NCT Number: NCT07731152

Evaluation of the Outcome of Septoplasty With or Without Inferior Turbinate Reduction

This prospective comparative study aims to evaluate the outcomes of septoplasty with or without inferior turbinate reduction in patients with symptomatic deviated nasal septum. Subjective and objective outcomes will be assessed using the NOSE score, Peak Nasal Inspiratory Flow (PNIF), and nasal endoscopic examination before and after surgery.

Not Yet Recruiting

Trial opening soon.

Get Notified

Key information

Conditions

Deviated Nasal Septum Airway Obstruction Nasal Obstruction Nasal Obstruction Septal Deviation Compensatory Inferior Turbinate Hypertrophy Nose Diseases Otorhinolaryngologic Diseases Respiration Disorders Respiratory Insufficiency Respiratory Tract Diseases

Age range

18 year–50 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

About this study

This prospective comparative study will be conducted at the Department of Otolaryngology, Sohag University Hospital. The study aims to compare the outcomes of septoplasty alone versus septoplasty combined with inferior turbinate reduction in adult patients with symptomatic deviated nasal septum and persistent nasal obstruction. Forty patients will be enrolled and allocated into two groups. Clinical outcomes will be evaluated preoperatively and at 1 month and 3 months postoperatively using the Nasal Obstruction Symptom Evaluation (NOSE) score, Peak Nasal Inspiratory Flow (PNIF), and diagnostic nasal endoscopy. The primary outcome is improvement in nasal obstruction symptoms, while secondary outcomes include changes in NOSE score, PNIF measurements, and endoscopic findings.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients with symptomatic deviated nasal septum causing persistent nasal obstruction, aged 18-50 years, who failed medical treatment for at least 3 months, will be included in the study.

Exclusion criteria

  • Patients with previous nasal surgery, nasal polyposis, chronic rhinosinusitis, alar collapse, uncontrolled allergic rhinitis, nasal tumors, or external nasal deformity requiring rhinoplasty will be excluded from the study.

Treatment and study plan

septoplasty

Procedure

Surgical correction of deviated nasal septum to relieve nasal obstruction.

septoplasty with inferior turbinate reduction.

Procedure

Surgical correction of deviated nasal septum combined with inferior turbinate reduction to improve nasal airflow and relieve obstruction.

Primary outcomes

  1. Improvement in nasal obstruction symptoms

    Time frame: Baseline (preoperative), 1 month postoperative, and 3 months postoperative

    Assessment of improvement in nasal obstruction symptoms after surgery using the Nasal Obstruction Symptom Evaluation (NOSE) score.

Secondary outcomes

  1. Change in NOSE score

    Time frame: Baseline, 1 month postoperative, and 3 months postoperative

    Comparison of NOSE score changes between patients undergoing septoplasty alone and those undergoing septoplasty with inferior turbinate reduction.

  2. Change in Peak Nasal Inspiratory Flow (PNIF)

    Time frame: Baseline, 1 month postoperative, and 3 months postoperative

    Objective assessment of nasal airflow improvement using Peak Nasal Inspiratory Flow measurement.

  3. Endoscopic nasal examination findings

    Time frame: Baseline, 1 month postoperative, and 3 months postoperative

    Assessment of postoperative nasal cavity findings by diagnostic nasal endoscopy.

Study contacts

Contact information is provided by the study sponsor or research team.

Mena Mikhael, M.B.B.Ch

CONTACT

[email protected]

01202886850

Sponsors and collaborators

Lead sponsor

Sohag University

Other

Registry information

Important dates

Study start
2026
Primary completion
2027
Study completion
2027
First posted
Jul 28, 2026
Registry last updated
Jul 28, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.