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NCT Number: NCT07025707

Comparison of Two Different Methods for Calculating Intraocular Lens Tilt and Decentration

Agreement and Reproducibility of Intraocular Lens Tilt and Decentration Measurements: A Comparison between CASIA2 and CILT

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Key information

Conditions

Intraocular Lens

Age range

21 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Krankenhaus der Barmherzigen Brüder Wien

Vienna, State of Vienna, 1020, Austria

Location status: Recruiting

Location contact

Konstantin Seiller-Tarbuk, Dr. med.

CONTACT

[email protected]

00431211215141

About this study

This prospective observational study evaluates the agreement and reproducibility of intraocular lens (IOL) tilt and decentration measurements obtained from two different imaging modalities: the CASIA2 anterior segment swept-source optical coherence tomography (AS-SS-OCT) system and the Calculator for Intraocular Lens Tilt (CILT) software, based on standardized anterior segment image analysis.

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • planned cataract surgery
  • agreement to participation

Exclusion criteria

  • Zonulolysis
  • Strabismus
  • Reduced Compliance
  • Axial length <20 or >25 mm
  • Keratokonus
  • PEX

Treatment and study plan

Primary outcomes

  1. Intraocular Lens Tilt (CASIA2 and CILT)

    Time frame: Measured during the pre-surgery examination under normal pupil conditions and after pharmacologic dilation (45 minutes post-mydriatic instillation).

    Intraocular lens (IOL) tilt, measured in degrees, assessed from anterior segment swept-source optical coherence tomography (AS-SS-OCT) images using the CASIA2 system and CILT software. Tilt is defined as the angle between the IOL plane and the corneal vertex.

  2. Intraocular Decentration (CASIA2 and CILT)

    Time frame: Measured during the pre-surgery examination under normal pupil conditions and after pharmacologic dilation (45 minutes post-mydriatic instillation).

    Intraocular lens (IOL) decentration, measured in micrometers, assessed from anterior segment swept-source optical coherence tomography (AS-SS-OCT) images using the CASIA2 system and CILT software. Decentration is defined as the distance between the IOL center and the corneal vertex.

Study contacts

Contact information is provided by the study sponsor or research team.

Konstantin Seiller-Tarbuk, Dr. med.

CONTACT

[email protected]

00431211215141

Sponsors and collaborators

Lead sponsor

St John of God Hospital, Vienna

Other

Registry information

Official study title

Agreement and Reproducibility of Intraocular Lens Tilt and Decentration Measurements: A Comparison Between CASIA2 and CILT

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Jun 17, 2025
Registry last updated
Jun 17, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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