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Completed

NCT Number: NCT03785002

Comparison of the Increment of Neuromuscular Parameters in Vegetarians and Non-vegetarians

A strength training session promotes increased muscle sensitivity to protein synthesis, which lasts for 24 hours after its closure. Recent studies have shown that the subsequent intake to the training session of approximately 20g or 0.24g / kg of high-quality protein in the same meal induces a plateau in this synthesis. Thus, this study aims to compare the muscular strength between vegetarian and omnivorous athletes with adequate protein intake to reach this plateau. It will recruit 64 university sportsmen who have maintained vegetarian or omnivorous diet for at least 6 months, totalizing 32 individuals per group. After signing the Term of Consent, participants will be submitted to anthropometric and body composition assessment (via DEXA), neuromuscular tests [(ie, muscle strength - 1RM, peak torque of knee extensors (JE), muscle thickness of JE and cohort analysis (ANCOVA) will be used in order to compare the results of the study, and to compare the results of the covariance analysis (ANCOVA). the levels of the neuromuscular parameters between the groups, considering the initial values of the force and the initial muscular thickness as covariables, the other parameters will be presented in the form of mean and standard deviation or median, the differences will be considered significant for values of p <0, 05. Expected to find no differences in strength and muscle thickness between vegetarians and omnivores after adequate protein intake.

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Key information

Conditions

Strength Training Dietary Proteins Hypertrophy Muscle Strength Pathological Conditions, Anatomical Pathological Conditions, Signs and Symptoms

Age range

19 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Gabriela Luccciana Martini

Porto Alegre, Rio Grande do Sul, Brazil

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Be over the age of 19 and under 60;
  • Have BMI <30 kg / m²;
  • Be vegetarian or omnivorous for at least 6 months;
  • Have not exercised regularly for at least 6 months.
  • Be available to practice bodybuilding at School of Physical Education, Physiotherapy and Dance, 2x / week, for 3 months, free (times to combine).

Exclusion criteria

  • Be vegan, vegetarian lacto or vegetarian egg
  • Be a carrier of chronic diseases;
  • Present physical limitations or musculoskeletal problems, which contraindicate the performance of strength exercises;
  • Failure to adhere to the proposed dietary modifications, relating to the adequacy of the portion of protein per meal, due to financial unfeasibility (low income condition);
  • Use of protein or amino acid, caffeine or other thermogenic food supplements.

Treatment and study plan

Strength training

Other

24 strength training sessions, with approximately 1 hour duration, that will occur 2x/week

Protein intake

Other

Guidance on the adequacy of protein intake (at least 20g of protein in breakfast, lunch and dinner)

Primary outcomes

  1. Muscle Thickness (mm)

    Time frame: At the14th week of study participation.

    To compare muscle thickness (mm) of the femoral quadriceps by Ultrasound, among vegetarian and omnivorous participants.

Secondary outcomes

  1. Maximal strength (kg)

    Time frame: At the 14th week of study participation.

    To compare maximal strength (kg), using the one- repetition maximum test (1RM) for bilateral knee extension exercises. Each subject's maximal load was determined with no more than five attempts and an adequate amount of recovery time was permitted between each attempt (3-5min). Each valid repetition was considered when subjects performed full knee extension with proper technique.

  2. Isometric peak torque (PTiso) (N.m)

    Time frame: At the 14th week of study participation.

    To compare knee extensors Isometric peak torque (N.m), defined as the highest value of the torque recorded during unilateral knee extension, using an isokinetic dynamometer, among vegetarian and omnivorous participants.

  3. Body fat free mass (g)

    Time frame: At the 14th week of study participation

    To compare body fat free mass by Dual-energy x-ray absorptiometry (DEXA) evaluation, of omnivorous and vegetarian participants.

  4. Body fat mass (g)

    Time frame: At the14th week of study participation.

    To compare body fat mass by Dual-energy x-ray absorptiometry (DEXA) evaluation, of omnivorous and vegetarian participants.

  5. Protein intake (g)

    Time frame: At the 14th week of study participation.

    To compare daily protein intake (g) assessed by 24 hour reminder, applied in interview conducted by nutritionist, of omnivorous and vegetarian participants.

Sponsors and collaborators

Lead sponsor

Hospital de Clinicas de Porto Alegre

Other

Registry information

Official study title

Comparison of Strength and Muscle Thickness of Recreational Sports Individuals With Vegetarian or Non-vegetarian Food Standards Adequate in Proteins

Important dates

Study start
2018
Primary completion
2019
Study completion
2019
First posted
Dec 24, 2018
Registry last updated
May 22, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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