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NCT Number: NCT06321263

Comparison of the Effects of Peripheral Muscle Training and Inspiratory Muscle Training in Geriatric Individuals

In geriatric individuals, there is a decrease in muscle strength, muscle mass and physical performance with ageing. These physiological changes occurring in geriatric individuals make maintaining the physical activity necessary for a healthy life difficult. Weakness of respiratory muscles in geriatric individuals can increase the prevalence of diseases and disability. It has been shown in the literature that peripheral muscle training and inspiratory muscle training increase exercise capacity similarly. The effectiveness of moderate-intensity peripheral muscle training and inspiratory muscle training in sarcopenic geriatric individuals was compared and found to have similar effects on muscle strength.

Our study aims to compare the effects of inspiratory and peripheral muscle training in addition to aerobic exercise on muscle strength, physical performance, respiratory muscle strength, functional capacity, sarcopenia, and quality of life.

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Key information

Conditions

Age range

65 year–80 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Golden Years Life Center

Çanakkale, Turkey (Türkiye)

Location status: Recruiting

Location contact

Sezen Uyanık

CONTACT

[email protected]

0 286 21 800 18 ext. 14006

About this study

Aging causes decline in physiological systems, including the cardiorespiratory system, musculo-skeletal system, vestibulo-ocular system, slowed postural control and cognitive function (especially dual task and executive functions). These changes occurring in geriatric individuals are an increased risk factor for various diseases and affect the individual's daily living activities, working life, addiction status and communication with the environment.

The most recommended physical activity subgroups in the guidelines for geriatric individuals are aerobic exercises, strengthening exercises, flexibility exercises and balance exercises. Physiological changes that occur in the organism during the aging process can cause muscle weakness, functional losses/limitations, balance problems, cognitive problems, chronic diseases and mortality. However, physiological and mechanical respiratory changes in geriatric individuals; It is known that there is a decrease in lung elasticity, respiratory muscle strength and chest wall compliance. These physiological changes make it difficult to maintain the physical activity necessary for a healthy life. It has also been shown that weakness of respiratory muscles in geriatric individuals can increase the rate of morbidity and mortality.

It is reported in the literature that respiratory muscle training (RMT) strengthens the diaphragm in geriatric individuals and may have a protective effect against respiratory tract infections by improving aerobic capacity, physical performance and coughing skill. In addition, studies have shown that Inspiratory Muscle Training (IMT) increases the strength of the inspiratory respiratory muscles, allows a more mechanically effective breathing pattern, and provides improvements in exercise capacity, diaphragm thickness and mobility, cardiac autonomic control and functional autonomy. Studies have shown that IMT is effective and applicable in improving balance ability. It has been reported to improve dynamic and reactive balance, as well as gait speed and inspiratory muscle function in healthy geriatric individuals. Considering the stated benefits of IMT, some authors suggest that it is an alternative or complementary training method that can be used for geriatric individuals, especially when other types of exercise are not possible, and that it should be added to rehabilitation programs.

In general, it has been reported in the literature that resistant exercise training is preferred as an intervention in geriatric individuals and that this training improves muscle strength, physical performance and functional performance. In a study where a high-intensity resistance training program was applied in sarcopenic geriatric women, it was reported that it increased respiratory muscle strength and Maximum Expiratory Pressure (MEP) and affected health-related quality of life.

There are opinions reported in the literature that improvement in peripheral and inspiratory muscle strength will reduce the risk of mortality. The effects of moderate-intensity peripheral muscle training and inspiratory muscle training were compared in sarcopenic geriatric individuals and were found to have similar effects on muscle strength. It has been reported that there is no significant change in muscle mass and physical performance. However, no study has been found in which the aerobic and strengthening exercises recommended for geriatric individuals are combined. In order to shed light on this deficiency in the literature, the investigators aim in our study to compare the effects of peripheral muscle training and inspiratory muscle training combined with aerobic training on muscle strength, physical performance, functional capacity and quality of life.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 65 years to 80 years (Older ),
  • Standardised Mini Mental Test score ≥ 20,
  • To walk 10 meters with or without an assistive device,
  • If the participants answered No all of the questions of The Physical Activity Readiness Questionnaire
  • Volunteering to participate in the study

Exclusion criteria

  • With serious neurological and orthopedic problems that may prevent them from exercising,
  • With serious vision and hearing problems,
  • With a psychiatric disease,
  • With serious cardiac and pulmonary system diseases that may prevent them from exercising,
  • With vestibular system problems or medication use that may affect the vestibular system,
  • Smokers.

Treatment and study plan

Peripheral Muscle Training and step aerobics training

Other

First 5-minute warm-up in the protocol (calisthenic exercises); 30-40 minutes of resistance exercises and step aerobic exercises and the last 5 minutes cooling (stretching exercises) period will be applied.

Other names: Peripheral Muscle Training

Inspiratory Muscle Training and step aerobics training

Other

First 5-minute warm-up in the protocol (calisthenic exercises); 30-40 minutes of resistance exercises and step aerobic exercises and the last 5 minutes cooling (stretching exercises) period will be applied.

Other names: Inspiratory Muscle Training

Primary outcomes

  1. The sociodemographic data form

    Time frame: Ten weeks

    Socio-demographic data of individuals (name-surname, age, gender, height,weight, smoking, occupation, education) will be collected with the demographic data collection form created by the researchers. In the clinical information section, other diseases and medications used will be recorded.

  2. Hand grip strength

    Time frame: Ten weeks

    Three consecutive measurements will be made on the dominant hand with a Jamar hand dynamometer, 1 minute apart, and the highest value will be recorded.

  3. Maximal inspiratory and expiratory pressures (MIP, MEP)

    Time frame: Ten weeks

    Static inspiratory (MIP) or expiratory (MEP) mouth pressures assess respiratory muscle strength.

  4. 6-Minute Walk Test (6MWT)

    Time frame: Ten weeks

    The 6MWT will be used to measure functional capacity.

  5. The Short Physical Performance Battery (SPPB)

    Time frame: Ten weeks

    SPPB is a set of tests that combine gait speed, chair stand, and balance measures. It is used to predict possible disability and monitor function in older individuals.

  6. Assessment of seniors᾽ quality of life: WHOQOL-OLD questionnaire

    Time frame: Ten weeks

    WHOQOL-OLD, a 24-item QOL measure, was developed by the WHOQOL Group as an add-on module to their QOL measures, specifically for use with older adults. A total score is the mean of the summed facet scores and ranges from one to five, with higher scores indicating better QOL.

Secondary outcomes

  1. SARC-F questionnaire

    Time frame: Ten weeks

    It is a rapid diagnostic test developed for sarcopenia. A SARC-F survey score ≥ 4 is important for the diagnosis of sarcopenia. SARC-F score range is from 0 to 10; 0-3 points represent healthy condition, 4 points and above represent symptomatic condition.

Other outcomes

  1. Canadian Occupational Performance Measure

    Time frame: Ten weeks

    The COPM will be used to identify the individual's activity performance problems and measure performance and satisfaction levels. A difference of 2 points from pre-test to post-test on either performance or satisfaction represents a clinically significant difference on the COPM.

Study contacts

Contact information is provided by the study sponsor or research team.

Buket Akıncı, Ass.Prof.

CONTACT

[email protected]

902124448276

Sezen Uyanık, MSc

CONTACT

[email protected]

902862180018 ext. 14006

Sponsors and collaborators

Lead sponsor

Biruni University

Other

Registry information

Official study title

Comparison of the Effects of Peripheral Muscle Training and Inspiratory Muscle: Randomized Clinical Study.

Important dates

Study start
2024
Primary completion
2024
Study completion
2025
First posted
Mar 20, 2024
Registry last updated
May 28, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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