Department of Periodontology and Oral Mucosa Diseases, Medical University of Warsaw
Warsaw, Masovian Voivodeship, 02-097, Poland
NCT Number: NCT06366295
The study aims to comparatively assess clinical parameters, biochemical and microbiological parameters after treatment of periodontitis using subgingival mechanotherapy traditional and subgingival mechanotherapy using a perioscope.
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Notify Me20 year–60 year
All sexes
Interventional
Not applicable
Warsaw, Masovian Voivodeship, 02-097, Poland
Non-surgical treatment is the basic form of disease treatment periodontitis. Its first stage is the mechanical removal of dental plaque along with the control of risk factors. Subgingival mechanotherapy, also known as scaling and root planing (SRP) is the next stage, aimed at the subgingival area. Perioscopy makes possible direct real-time visualization of the root surface during the procedure. The research results published so far indicate improvement or no significant differences clinical parameters after SRP procedure using a perioscope vs traditional subgingival instrumentation. The aim of this study is to indicate, or not, clinical, biochemical (level of pro-inflammatory cytokines) and microbiological (A. actinomycetemcomitans, P. gingivalis, T. denticola) differences after periodontitis treatment using the traditional method vs. using a perioscope.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Subgingival mechanotherapy using a machine scaler, curettes and a perioscope
Subgingival mechanotherapy using a machine scaler and curettes
Time frame: 0 (before), 3 and 6 months after SRP
Distance from the gingival margin to the bottom of the gingival sulcus
Time frame: 0 (before), 3 and 6 months after SRP
Distance from the cementoenamel junction to the bottom of the gingival sulcus
Time frame: 0 (before), 3 and 6 months after SRP
Percentage of sites with bleeding provoked by applying a probe to the bottom of a sulcus/pocket.
Time frame: 0 (before), 3 and 6 months after SRP
Percentage of sites with plaque
Time frame: 0 (before), 3 and 6 months after SRP
Distance between the most apical point of gingival margin and the mucogingival junction
Time frame: 0 (before), 3 and 6 months after SRP
Thickness of the gingiva measured 2 mm apical to the gingival margin
Time frame: 0 (before) and 6 months after SRP
Levels of periodontal pathogens (Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Treponema denticola) measured with real-time polymerase chain reaction (RT-PCR) test; data presented as number of bacteria of these species and percentage of total bacteria found in a sample; sample taken from the deepest pocket on each side.
Time frame: 0 (before), 3 and 6 months after SRP
Levels of (IL - interleukin) IL-1β, IL-6, IL-8, IL-10 and interferon-gamma in gingival crevicular fluid presented as pg/ml; sample taken from the deepest pocket on each side.
Medical University of Warsaw
Other
Subgingival Mechanotherapy Using a Periodontal Endoscope Compared to Classical Subgingival Mechanotherapy for the Treatment of Periodontitis: a Randomized Clinical Trial
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