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Completed

NCT Number: NCT00575354

Comparison of Sevoflurane and Isoflurane Anesthesia for Benign Breast Tumor Excision

Generally, benign breast tumors are excised under the local anesthesia. But such action was so invasive that every patient would experience the physiological and psychological stimuli unavoidably. Sevoflurane was advised as a better inhalational anesthesic for its "easy come,easy go" property during short-lasting operations than isoflurane. We purposed that sevoflurane would be a superior anesthesic for benign breast tumor excision than isoflurane with relative less alteration in hemodynamics, less postoperative side effects and easily-control the depth of anesthesia.

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Key information

Age range

18 year–64 year

Sex eligibility

Female

Study type

Interventional

Phase

Phase 4

Primary location

Nanjing Maternal and Child Care Hospital

Nanjing, Jiangsu, 210004, China

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Chinese
  • Diagnosed benign breast tumor patients
  • 18-64 yrs

Exclusion criteria

  • Allergic to any interventional drugs
  • Organic dysfunction
  • Long-lasting PACU staying

Treatment and study plan

Sevoflurane

Drug

3-6% sevoflurane inhaled for anesthesia induction, and 2-3% sevoflurane was used to maintain the anesthesia till the end of the operation.

Other names: Sevofrane

Isoflurane

Drug

3-6% isoflurane inhaled for anesthesia induction, and 2-3% isoflurane was used to maintain the anesthesia till the end of the operation.

Primary outcomes

  1. Time of induction, maintenance and resuscitation

    Time frame: 0h to the end of the operation

Secondary outcomes

  1. Intraoperative hemodynamics; Postoperative side effects;

    Time frame: 0h to 24h after the end of the operation

Sponsors and collaborators

Lead sponsor

Nanjing Medical University

Other

Registry information

Official study title

Anesthesia With Sevoflurane and Isoflurane for Excision Surgeries in Benign Breast Tumors

Acronym: CSIABTEC

Important dates

Study start
2007
Primary completion
2007
Study completion
2007
First posted
Dec 18, 2007
Registry last updated
Apr 21, 2008

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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