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Completed

NCT Number: NCT06167343

Comparison of Semitendinosus and Quadriceps Grafts for Anterior Cruciate Ligament Reconstruction

To investigate the differences between the two methods for reconstruction of the anterior cruciate ligament (ACL), to support the development of the best method for young federated male football players. After surgery with quadricipital tendon graft or semitendinosus tendon graft, a two-year follow-up and the rate of return to sport are proposed.

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Key information

Conditions

ACL ACL Injury Anterior Cruciate Ligament Injuries Knee Injuries Leg Injuries Wounds and Injuries

Age range

14 year–40 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Faculty of Health Sciences

Granada, 18071, Spain

About this study

The anterior cruciate ligament is one of the most common traumatic injuries in football, and surgery is proposed to restore knee stability. However, following surgery, few studies have focused on functional recovery of the knee with a wide arsenal of physical tests. Therefore, this study aims to study the efficacy for young football players of two types of grafts based on the most common tendons, the quadricipital and the semitendinosus (without the semimembranosus). Follow-ups will be performed at three months, six months, one year and two years after reconstruction. The variables measured will be isokinetic strength of flexors and extensors, unipodal jump test, self-perceived function, pain and tendon architecture with ultrasound.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Confirmed anterior cruciate ligament rupture by MRI.
  • Prognosis of anterior cruciate ligament reconstruction surgery.
  • Be a registered or recreational football player.

Exclusion criteria

  • Previous knee surgery.
  • Having articular cartilage lesions of Outerbridge grade greater than III-IV.

Treatment and study plan

ACL reconstruction

Procedure

In addition to surgical reconstruction, any structures that may have been injured concomitantly (meniscus, other ligament) will be repaired in the same surgery.

Primary outcomes

  1. Lower limb strength

    Time frame: Participants will be followed over 24 months

    assessed by an isokinetic test with an isokinetic dynamometer (HUMAC NORM)

  2. Horizontal hop test

    Time frame: Participants will be followed over 24 months

    assessed by horizontal jump with one leg and hands on the waist, measured with a centimetric tape (three jumping opportunities)

Secondary outcomes

  1. Self-reported functionality

    Time frame: Participants will be followed over 24 months

    assessed by Tegner Lysholm Knee Scoring Scale and Modified Cincinnati Rating System Questionnaire (Spanish version)

  2. Knee pain

    Time frame: Participants will be followed over 24 months

    assessed by Visual Analogue Scale (VAS) for knee pain. The subjective perception of pain from 0 to 10 will be registered. Higher scores mean a worse outcome.

  3. Pressure pain threshold

    Time frame: Participants will be followed over 24 months

    Using a digital algometer in epicondyle, vastus lateralis, vastus medialis and quadricipitalis tendon, patellar tendon, and insertion of the semitendinous tendon

  4. Tendon ultrasound

    Time frame: Participants will be followed over 24 months

    it will monitor the morphology of the tendon and their surgical gap using ultrasound (Samsung HM70A echograph and Samsung Phased Array PE2-4 probe)

  5. Perimeters

    Time frame: Participants will be followed over 24 months

    measured with the volume of both legs (injured and uninjured) using the mid-thigh circumference.

Sponsors and collaborators

Lead sponsor

Universidad de Granada

Other

Collaborators

  • Hospital Vithas

Registry information

Official study title

Examining Anterior Cruciate Ligament Reconstruction With Quadriceps- vs. Semitendinosus Tendon Graft for Young Federated Male Football Players.

Important dates

Study start
2023
Primary completion
2025
Study completion
2025
First posted
Dec 12, 2023
Registry last updated
May 6, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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