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NCT Number: NCT07442188

Comparison of Postoperative Analgesic Effects of Quadro-iliac Plane Block and Transversus Abdominis Plane Blocks in Inguinal Hernia Surgery

Inguinal hernia repair is one of the most commonly performed surgical procedures worldwide. Despite being classified as a minor surgical intervention, moderate to severe postoperative pain is reported in approximately 60% of patients. In a subset of these patients, acute postoperative pain may persist and evolve into chronic post-surgical inguinal pain, significantly affecting quality of life.

In recent years, beyond the use of systemic intravenous analgesics, ultrasound-guided fascial plane blocks have been increasingly incorporated into multimodal analgesia protocols with the aim of reducing postoperative opioid consumption and improving pain control. However, the current literature does not provide definitive evidence regarding the superiority of one block technique over another in this surgical population.

The primary objective of the present study is to compare the analgesic efficacy of the Quadro-iliac Plane Block (QIPB) and the transversus abdominis plane block (TAPB) in patients undergoing inguinal hernia repair.

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Key information

Conditions

Peripheral Nerve Block Agnosia Hernia Hernia, Abdominal Hernia, Inguinal Nervous System Diseases Neurobehavioral Manifestations Neurologic Manifestations Pain Management Pathological Conditions, Anatomical Pathological Conditions, Signs and Symptoms Perceptual Disorders Signs and Symptoms

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients aged between 18 and 65 years
  • Patients with an American Society of Anesthesiologists (ASA) physical status classification of I-III.
  • Patients with a body mass index (BMI) between 18 and 30 kg/m².
  • Patients scheduled to undergo unilateral inguinal hernia repair under general anesthesia in the operating room.

Exclusion criteria

  • Patients younger than 18 years or older than 65 years.
  • Patients with an ASA physical status classification of IV or higher.
  • Patients with advanced comorbidities.
  • Patients with a history of bleeding diathesis.
  • Patients with infection at the site of the planned procedure.
  • Patients with a BMI below 18 kg/m² or above 30 kg/m².

Treatment and study plan

TAPB

Procedure

Patients will undergo TAPB procedure using 30 ml of 0.25% bupivacaine under ultrasound guidance.

QIPB

Procedure

Patients will undergo QIPB procedure using 30 ml of 0.25% bupivacaine under ultrasound guidance.

Primary outcomes

  1. Pain Score

    Time frame: Up to 24 hours

    Pain will be assessed using a visual analog scale from 0 mm (no pain) to 100 mm (worst pain) at rest and when coughing. Pain assessment will be made at 0, 1, 6, 12, 18, and 24 hours after surgery.

Secondary outcomes

  1. Patient Satisfaction

    Time frame: 24th hour

    Quality of recovery-15 (QoR-15) score was used as the satisfaction score. The patient-reported Turkish QoR-15 score includes 15 questions that evaluate the patient's postoperative recovery. The QoR-15 score is grouped under two groups, A and B. A high QoR-15 score, a score between 0 (poor) and 10 (excellent) for each item, and a total score of 150 indicate better quality of recovery.

Study contacts

Contact information is provided by the study sponsor or research team.

Ibrahim Topcu, MD

CONTACT

[email protected]

+905437860316

Musa Zengin, Associate Professor

CONTACT

[email protected]

+905307716235

Sponsors and collaborators

Lead sponsor

Ankara Etlik City Hospital

Other Gov

Registry information

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Mar 2, 2026
Registry last updated
Jun 3, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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