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NCT Number: NCT06520943

Comparison of Minimum Flow and Low Flow Desflurane Anesthesia in Robotic Assisted Laparoscopic Abdominal Surgery

This study aims to compare the use of low fresh gas flow (1 L/min) desflurane anesthesia with minimum fresh gas flow (0.5 L/min) desflurane anesthesia in patients undergoing robotic-assisted abdominal surgery. The comparison will be based on hemodynamic and respiratory parameters. The secondary aim of our study is to compare the two different fresh gas flow methods in terms of inhalation agent consumption and soda lime consumption.

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Key information

Conditions

Minimal Flow Anesthesia Low Flow Anesthesia Robotic Assisted Laparoscopic Abdominal Surgery

Sex eligibility

All sexes

Study type

Observational

Primary location

Ankara City Hospital

Ankara, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients undergoing robotic-assisted abdominal surgery

Exclusion criteria

  • serious cardiac, respiratory, hepatic, renal, or mental disorders;
  • hearing problems;
  • anxiety, depression, or other psychiatric conditions;
  • patient's request to leave the study

Treatment and study plan

blood gas analysis

Other
  • Airway pressure (P plateau, Ppeak) values are taken from the anesthesia device data,
  • BIS (from routine BIS monitoring)
  • Temperature (routinely from pharyngeal temperature probe),
  • Oxygen saturation (routinely from the patient monitor)
  • End-tidal CO₂,
  • inspiratory O₂ concentration,
  • Inspiratory CO2 concentration,
  • inspiratory and expiratory desflurane concentrations,
  • tidal volume,
  • MAC is routinely obtained from anesthesia device data.
  • Blood Gas Analysis (COHgb, Ph, PO2, PCO2, SaO2, HCO3, Base deficit, glucose, lactate)

Primary outcomes

  1. inspiratory O2 concentration

    Time frame: from beginning of anesthesia induction to the end of anesthesia (during periopertaive period)

    inspiratory O2 concentration is measured from anesthesia machine monitor

  2. partial oxygen pressure

    Time frame: from beginning of anesthesia induction to the end of anesthesia (during periopertaive period)

    PO2 from blood gas analysis

Secondary outcomes

  1. desflurane consumption

    Time frame: 3th hour

    desflurane consumption

  2. changes in liver and kidney function tests from the preoperative values to 48 hours postoperative

    Time frame: postoperative 1st day

    to determine the changes in serum aspartate aminotransferase (AST), alanine aminotransferase (ALT), blood urea nitrogen (BUN), and creatinine from the preoperative values to 48 hours postoperative

Study contacts

Contact information is provided by the study sponsor or research team.

Betül Güven Aytaç

CONTACT

[email protected]

+903125662200

Sponsors and collaborators

Lead sponsor

Ankara City Hospital Bilkent

Other

Registry information

Official study title

Comparison of Minimum Flow Desflurane Anesthesia With Respiratory Parameters and Blood Gas Analyses and Low Flow Desflurane Anesthesia in Robotic Assisted Laparoscopic Abdominal Surgery

Important dates

Study start
2024
Primary completion
2024
Study completion
2024
First posted
Jul 25, 2024
Registry last updated
Jul 25, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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