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NCT Number: NCT07460115

Comparison of Mean Duration of Analgesia Following the Administration of Bupivacaine With and Without Magnesium Sulphate in Ultrasound Guided Erector Spinae Plane Block in Modified Radical Mastectomy Patients

To compare mean duration of postoperative analgesia following the administration of bupivacaine with and without magnesium sulphate in erector spinae plane block in modified radical mastectomy patients.

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Key information

Conditions

Modified Radical Mastectomy

Age range

25 year–60 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Gulab Devi Hospital Ferozpur Road Lahore

Lahore, Punjab Province, 54600, Pakistan

About this study

There is a difference in mean duration of analgesia following the administration of bupivacaine with and without magnesium sulphate in erector spinae plane block in modified radical mastectomy patients.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Female patients having ASA 1 and Il being aged 2 5 - 60 years and undergoing one sided breast cancer surgery * Patients who sign written informed consent to participate in the study.

Exclusion criteria

  • Patients having contraindications for regional blocks (c.g., infection a t the injection site, coagulopathy), allergy to the drugs used i n the study Patients who received radiotherapy, and patients need axillary dissection • Patients with known hypersensitivity to local anesthetic drug (Bupivacaine). Patients with coagulation disorders or receiving anti-coagulant therapy (INR>2.0).

Treatment and study plan

Group B (bupivacaine)

Drug

receive 20 ml of 0.25% bupivacaine on the operated side for the Erector Spinae Plane (ESP) block.

Other names: Group bupivacaine

Bupivacaine plus magnesium sulfate

Drug

20 ml of 0.25% bupivacaine plus 250 mg of magnesium sulfate on each side.

Primary outcomes

  1. post-operative analgesia

    Time frame: 20 minutes

    There is a difference in mean duration of analgesia following the administration of bupivacaine with and without magnesium sulphate in erector spinae plane block in modified radical mastectomy patients.

Sponsors and collaborators

Lead sponsor

Gulab Devi Hospital

Other

Registry information

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Mar 10, 2026
Registry last updated
Mar 10, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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