Skip to main content
OpenTrials
Completed

NCT Number: NCT05427968

Comparison of Hypotension During Spinal Anaesthesia for C-section

Maternal hypotension during C section has been reported due to aortocaval compression (ACC) by full term uterus in supine position. This study aimed at reporting the effect of left tilt on maternal hemodynamics.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Hypotension Aortocaval Compression Cardiovascular Diseases Cesarean Section Vascular Diseases

Sex eligibility

Female

Study type

Observational

Primary location

Rawalpindi Medical University

Rawalpindi, Punjab Province, 46000, Pakistan

About this study

C-section is usually done in either general anesthesia or regional (epidural or spinal) anesthesia. The choice lies with the mother. In spinal anesthesia the anaesthetic agent is injected into the subarachnoid space. Hypotension in supine position that is associated with full term gravid uterus has been explained by compression of inferior venacava (IVF) and aorta. This aortocaval compression (ACC) can also cause hypotension during C- section after spinal block.

The aim of our study was to study the effect of left tilt on systolic (SBP) and diastolic blood pressure (DBP), heart rate and the frequency of phenylephrine used to maintain the blood pressure in normal range.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Participants ≥ 18 years, undergoing Elective Caesarean Section for term singleton pregnancy, ASA I/II, were included after their consent for the participation of the study.

Exclusion criteria

  • Participants with co-morbidities (Hypertension, diabetes mellitus, cardiovascular or cerebrovascular disease and a history of coagulation disorders), any contraindication to spinal anesthesia, with multiple pregnancy, pre-eclampsia, obesity (body mass index > 30 kg.m2), intrauterine growth were excluded from the study.

Treatment and study plan

Primary outcomes

  1. Group 1 - Supine Group

    Time frame: December 2021 to February 2022

    Systolic blood pressures decreased significantly in the supine group

  2. Group 2 - Left tilt Group

    Time frame: December 2021 to February 2022

    The decrease in the diastolic blood pressure was marginally significant in the left tilt group.

Sponsors and collaborators

Lead sponsor

Rawalpindi Medical College

Other

Registry information

Official study title

To Tilt or Not to Tilt?: Comparison of Severity of Hypotension Between Supine and Left Tilt Position During Spinal Anesthesia for Elective C-section

Important dates

Study start
2021
Primary completion
2022
Study completion
2022
First posted
Jun 22, 2022
Registry last updated
Jun 22, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.