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Completed

NCT Number: NCT05509764

The Effect of Oxygen Therapy on Atelectasis

In pregnancy, cephalal shift of the diaphragm caused by the enlarged uterus reduces the functional residual capacity and may increase the closure volume and predispose the pregnant woman to airway closure, leading to atelectasis. The development of atelectasis due to dermatomes retained in spinal anesthesia and intraoperative supine position may increase further. Oxygen therapy to be applied may also lead to absorption atelectasis by causing hyperoxia. The aim of our study is to evaluate the effect of oxygen support on the lungs in cesarean section operations under spinal anesthesia by lung ultrasound score and oxygen reserve index.

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Key information

Conditions

Atelectasis Cardiovascular Diseases Cesarean Section Hypotension Lung Diseases Pulmonary Atelectasis Respiratory Tract Diseases Vascular Diseases

Age range

18 year–47 year

Sex eligibility

Female

Study type

Observational

Primary location

Manolya Alkan, Zonguldak, Kozlu, Turkey (Türkiye)

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Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 18-50 years old
  • ASA I-II
  • Patients scheduled for elective cesarean section under spinal anesthesia

Exclusion criteria

  • alcohol or drug addiction, chronic obstructive pulmonary disease, cardiovascular disease, smokers anemia, liver or kidney disease, coagulation disorders allergic to anesthetic agents, sepsis or bacterial infection, body temperature is below 35°C and above 38°C Multiple pregnancy Preoperative hypoxemia SpO2<94% Diabetes mellitus Hypertension Placenta previa Premature rupture of membranes Intrauterine growth retardation Preeclampsia-eclampsia-fetal distress Polyhydramnios Morbid obesity BMI>45

Treatment and study plan

Lung Ultrasound Score

Diagnostic Test

determination of atelectasis by lung ultrasound score

Primary outcomes

  1. atelectasis

    Time frame: during the surgery

    measuring atelectasis due to oxygen therapy

Secondary outcomes

  1. APGAR score

    Time frame: 1st and 5th min after delivery

    baby status after delivery

  2. hypotension

    Time frame: during surgery

    maternal hypotension

Sponsors and collaborators

Lead sponsor

Zonguldak Bulent Ecevit University

Other

Registry information

Official study title

Evaluation of Oxygen Threapy by Lung Ultrasound and Oxygen Reserve Index in Patients Undergoing Cesarean Section Under Spinal Anesthesia

Important dates

Study start
2021
Primary completion
2022
Study completion
2022
First posted
Aug 22, 2022
Registry last updated
Aug 26, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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