Comparison of Eversion and Conventional Techniques in Carotid Endarterectomy

Atherosclerotic carotid artery disease is responsible for approximately 20% of strokes worldwide, and its treatment options include medical therapy, surgery, and stenting.Surgical management is prioritized over medical and stent based approaches and can be performed using either the conventional methed closed primarily or with a patch or the eversion technique.The aim of this study was to compare the intraoperative and early postoperative outcomes of the eversion technique and the conventional method with primary closure.

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Key information

Conditions

Atherosclerosis Occlusive Disease Brain Diseases Brain Ischemia Cardiovascular Diseases Central Nervous System Diseases Cerebrovascular Disorders Endarterectomy, Carotid Ischemic Attack, Transient Nervous System Diseases Stroke Stroke (CVA) or Transient Ischemic Attack Vascular Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital

Istanbul, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

-Patients undergoing isolated carotid endarterectomy, either emergently or electively

Exclusion criteria

Patients younger than 18 years of age
Patients scheduled for concomitant cardiac surgery
Reoperations

Treatment and study plan

Carotid endarterectomy, conventional

Procedure

In this study, patients were divided into two groups according to whether they underwent conventional or eversion endarterectomy. Although the eversion technique is the oldest method, the conventional approach is still widely performed due to its ease of application, despite not being recommended in current guidelines. Therefore, our aim is to contribute to the literature by comparing these two methods. The conventional method is performed with a longitudinal incision extending from the common carotid artery (CCA) to the internal carotid artery (ICA) up to the end of the plaque. The arteriotomy is then closed either primarily or with the use of a patch. In our study, we performed only the primary closure method..

Carotid endarterectomy, eversion

Procedure

In this study, patients were divided into two groups according to whether they underwent conventional or eversion endarterectomy. Although the eversion technique is the oldest method, the conventional approach is still widely performed due to its ease of application, despite not being recommended in current guidelines. Therefore, our aim is to contribute to the literature by comparing these two methods.The eversion method is performed by transecting the internal carotid artery (ICA) from the common carotid artery (CCA). The arteriotomy is then closed in an end to side fashion.

Primary outcomes

Number of participants with stroke and death

Time frame: 30 days

All strokes and/or deaths occurring within 30 days after surgery
Number of participants with symptoms of occlusion

Time frame: Postoperative 30 days

Early carotid restenosis or occlusion within 30 days after surgery

Sponsors and collaborators

Lead sponsor

Kastamonu University

Other

Registry information

Official study title

Comparison of Operative and Early Postoperative Outcomes Between Eversion and Conventional Techniques in Carotid Endarterectomy

Important dates

Study start: 2025
Primary completion: 2025
Study completion: 2025
First posted: Dec 17, 2025
Registry last updated: Jan 6, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed