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NCT Number: NCT07021651

COMPARISON OF ERECTOR SPINA PLAN BLOCK AND THORACIC PARAVERTEBRAL BLOCK FOR PERIOPERATIVE ANALGESIA

The primary aim of this study was to compare the postoperative analgesic efficacy of thoracic paravertebral block with erector spinae plane block, which we use in thoracotomy surgeries. Secondary aims were to compare these groups in terms of Riker Agitation-Sedation Scale (RASS) scores, postoperative complications, postoperative opioid consumption, and patient satisfaction.

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Key information

Conditions

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Health Sciences University Gazi Yaşargil Training and Research Hospital

Kayapınar, Di̇yarbakir, Turkey (Türkiye)

Location contact

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients who will undergo thoracotomy and are between the ages of 18-65
  • have American Society of Anesthesiologists (ASA) risk classification I-II will be included in the study.

Exclusion criteria

  • Patients who did not agree to participate in the study,
  • had an infection in the application area,
  • had coagulopathy,
  • were morbidly obese (Body mass index (BMI)>35),
  • had drug allergy,
  • had chronic pain, long-term opioid use, psychiatric illness history, and required emergency surgery were excluded from the study.

Treatment and study plan

Erector Spinae Plane (ESP) block admistring

Procedure

In the ESPB group, the probe was placed longitudinally at the level of the T5 transverse process, 2-3 cm lateral from the midline. The muscles were visualized superior to the transverse process ; then, the needle was inserted in the craniocaudal direction using the in-plane technique. A dose of 2 mL normal saline were injected into the two layers of the interfacial area under the erector spinae muscle, and the proper injection site was confirmed. After visualizing the linear spread of saline in the fascial plane, 20 mL of 0.25% bupivacaine was injected there for the block.

Thoracic Paravertebral Block administring

Procedure

In the TPVB group, the probe was placed 2-3 cm laterally and vertically of the T5 spinous process. Once the transverse process, corresponding paravertebral space, internal intercostal membrane, and pleura was identified , the needle was inserted in the lateromedial direction using the in-plane technique. After confirmation of pleural displacement with 2 mL saline, 20 mL of 0.25% bupivacaine was administered for the block.

Primary outcomes

  1. Numeric Rating Scale

    Time frame: Post-operative 30 minutes, 2 hours, 6 hours, 12 hours, 24 hours

    They will be numbered from 1 to 10. If reporting a score on a scale, please include the unabbreviated scale title, the minimum and maximum values, and whether higher scores mean a better or worse outcome.

Secondary outcomes

  1. Riker Agitation and Sedation Scale

    Time frame: Immediately after extubation

    7 Dangerous Agitation ... If reporting a score on a scale, please include the unabbreviated scale title, the minimum and maximum values, and whether higher scores mean a better or worse outcome.

  2. Patient satisfaction score:

    Time frame: Post-operative 30 minutes

    Patients' satisfaction with the quality of pain management will be assessed on the second postoperative day using the following scale: 1 = very dissatisfied; 2 = quite dissatisfied; 3 = moderate; 4 = quite satisfactory; 5 = very satisfactory.)

  3. 24-hour Tramadol usage:

    Time frame: posoperative 24 hours

    Amount of Tramadol used per 24 hours

Study contacts

Contact information is provided by the study sponsor or research team.

Hülya Tosun Söner, doktor

CONTACT

[email protected]

+905352792102

Sponsors and collaborators

Lead sponsor

Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital

Other

Registry information

Official study title

A Two-Center Randomized Controlled Trial

Acronym: A Two-Center

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Jun 15, 2025
Registry last updated
Jun 15, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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