Skip to main content
OpenTrials
Completed

NCT Number: NCT07712224

Comparison of Epidural and Intravenous Analgesia in Laparoscopic Sleeve Gastrectomy Patients

This retrospective observational study aimed to compare the effects of epidural analgesia and intravenous analgesia on early postoperative pulmonary function in patients undergoing laparoscopic sleeve gastrectomy. Preoperative and postoperative pulmonary function tests, pain scores, opioid consumption, and intraoperative respiratory parameters were evaluated.

Completed

Looking for future studies?

Notify Me

Key information

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Trabzon Kanuni Training and Research Hospital

Trabzon, Turkey (Türkiye)

About this study

This retrospective observational study was conducted at Trabzon Kanuni Training and Research Hospital. Adult patients who underwent laparoscopic sleeve gastrectomy between January 2025 and October 2025 were included. Patients were divided into two groups according to postoperative analgesia technique: epidural analgesia and intravenous analgesia.

The primary outcome was postoperative change in FEV1 at 24 hours after surgery. Secondary outcomes included changes in FVC and FEV1/FVC ratio, postoperative pain scores, additional opioid consumption, and intraoperative ventilatory parameters including peak airway pressure and plateau pressure.

Demographic data, perioperative variables, pulmonary function test results, arterial blood gas analyses, and analgesia-related data were retrospectively collected from hospital records. The study was approved by the Non-Interventional Scientific Research Ethics Committee of Trabzon University Faculty of Medicine.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adult patients aged 18-65 years
  • ASA physical status III
  • Undergoing laparoscopic sleeve gastrectomy
  • Availability of preoperative and postoperative pulmonary function tests
  • Availability of arterial blood gas analysis data
  • Receipt of epidural or intravenous postoperative analgesia

Exclusion criteria

  • Missing pulmonary function test data
  • Incomplete medical records
  • Conversion to open surgery
  • Severe respiratory disease affecting pulmonary function assessment

Treatment and study plan

Epidural analgesia (0.125% bupivacaine/2mcg fentanyl solution)

Procedure

Thoracic epidural catheter-based analgesia using bupivacaine and fentanyl for postoperative pain management.

Intravenous analgesia

Drug

Intravenous tramadol-based patient-controlled analgesia for postoperative pain management.

Primary outcomes

  1. Change in FEV1 at 24 Hours After Surgery

    Time frame: Preoperative period and postoperative 24 hours

    Assessment of postoperative change in forced expiratory volume in 1 second (FEV1) measured before surgery and at postoperative 24 hours.

Sponsors and collaborators

Lead sponsor

Trabzon Kanuni Education and Research Hospital

Other

Registry information

Official study title

Comparison of the Effects of Epidural and Intravenous Analgesia on Postoperative Lung Functions in Patients Undergoing Laparoscopic Sleeve Gastrectomy Surgery

Acronym: EAvs IV in LSG

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Jul 17, 2026
Registry last updated
Jul 17, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.