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Completed

NCT Number: NCT03706196

Comparison of Environmental Factors Between the Areas of Over- and Under-incidence of Crohn's Disease in the Haut de France Region, by the Study of Dental Exposomes

the aim of this preliminary observational study is to compare external exposomes from 10 teeth issued through 10 subjects living in high incidence of crohn's disease area and 10 teeth issued through 10 subjects living in low incidence of crohn's disease area.

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Key information

Conditions

Environmental Exposure

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

CHU lille

Lille, 59037, France

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • adults subjects living in high and low incidence of crohn's disease areas and needing a dental extraction for medical indication

Exclusion criteria

  • smokers during 10 last years

Treatment and study plan

Primary outcomes

  1. comparison of aluminum rate using metabolomic method in teeth between subjects living in high and low incidence crohn's disease areas.

    Time frame: Baseline: one session

Secondary outcomes

  1. comparison of environmental exposomes using metabolomic method in teeth between subjects living in high and low incidence crohn's disease areas.

    Time frame: Baseline: one session

Sponsors and collaborators

Lead sponsor

University Hospital, Lille

Other

Registry information

Acronym: EXPOSOMES

Important dates

Study start
2019
Primary completion
2019
Study completion
2019
First posted
Oct 15, 2018
Registry last updated
Dec 26, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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