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OpenTrials
Completed

NCT Number: NCT01387620

Comparison of DisCoVisc and Hydroxypropylmethylcellulose 2%

This prospective study was performed to compare two ophthalmic viscosurgical devices, DisCoVisc (hyaluronic acid 1.6% - chondroitin sulfate 4.0%) and hydroxypropylmethylcellulose 2% in terms of their overall clinical performance during phacoemulsification.

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Key information

Conditions

Corneal Edema Corneal Diseases Eye Diseases Intraocular Pressure

Age range

50 year–90 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

University of São Paulo

São Paulo, 05403-000, Brazil

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Bilateral age-related cataract
  • Grade 1-3 lens opacities classification system (LOCS III)
  • Pupil dilatation greater than 7.0 mm

Exclusion criteria

  • Black, brunescent, traumatic or subluxated cataract
  • Corneal endothelial disease (endothelial cell count less than 2.000 cells/mm3)
  • Glaucoma, uveitis
  • Previous ocular surgery

Treatment and study plan

Hyaluronic Acid and hydroxypropylmethylcellulose

Drug

Hyaluronic Acid 1.6% was used to performed phacoemulsification in one eye and hydroxypropylmethylcellulose 2% was used in the fellow eye.

Primary outcomes

  1. Corneal endothelial cell count

    Time frame: 6 months

Secondary outcomes

  1. Central Corneal Thickness

    Time frame: 7 days

Sponsors and collaborators

Lead sponsor

University of Sao Paulo

Other

Registry information

Official study title

Intraindividual Randomized Clinical Comparison of DisCoVisc and Hydroxypropylmethylcellulose 2% in Phacoemulsification

Important dates

Study start
2009
Primary completion
2010
Study completion
2010
First posted
Jul 4, 2011
Registry last updated
Jul 4, 2011

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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