Pakistan Air Force (PAF) hospital/Fazaia Post Graduate Medical Institute
Islamabad, Punjab Province, 44000, Pakistan
NCT Number: NCT07605273
There is a lack of data to determine the comparative advantages of 5% hypertonic saline and 3% hypertonic saline over the other. Hence, the current study was planned to determine their comparative effectiveness by comparing the change in means of central corneal thickness in the groups receiving 3% hypertonic saline and 5% hypertonic saline eyedrops developing post-phacoemulsification corneal edema.
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Notify Me18 year–65 year
All sexes
Interventional
Not applicable
Islamabad, Punjab Province, 44000, Pakistan
Although corneal edema and the associated visual impairment after cataract surgery are temporary, it is still a reason for discomfort for the patient. It is therefore absolutely necessary that the patient be counselled regarding the risk of developing corneal edema after phacoemulsification. Several international studies have demonstrated the effectiveness of 5% hypertonic saline in improving visual acuity and reducing corneal thickness through clinical and pachymetric assessments. However, similar research has yet to be conducted in the Pakistani population. The findings of this study would add to the existing literature and also help clinicians to opt for the better choice of care in achieving patients' good outcomes.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Patients received 5% hypertonic saline 2 hourly for the first 24 hours and then four times daily for the next 6 days.
Patients received 3% hypertonic saline 2 hourly for the first 24 hours and then four times daily for the next 6 days.
Time frame: 6 days
Post-treatment central corneal thickness in micrometer was compared between the two groups.
Muhammad Aamir Latif
Other
Effectiveness of 5% Hypertonic Saline Versus 3% Hypertonic Saline in Resolution of Corneal Edema in Post-operative Phacoemulsification Patients at the Department of Ophthalmology, Pakistan Air Force Hospital Islamabad.
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