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Completed

NCT Number: NCT00131521

Comparison of Different Mucoactive Agents for the Care of the Intubated Patient in a Surgical Trauma Intensive Care Unit

This study compares N-acetylcysteine (mucomyst) and sodium chloride to determine their efficacy in the prevention of pulmonary mucus obstruction and retention in intubated patients admitted to the surgical trauma intensive care unit (STICU).

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Key information

Conditions

Mucus Obstruction Intubation

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Univesity Hospital

San Antonio, Texas, 78229, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Intubated and admitted to the Surgical Trauma Intensive Care Unit (STICU)
  • Subjects must be eligible to start treatment within 24 hours of their initial intubation

Exclusion criteria

  • Patient anticipated to be extubated within 24 hours following STICU admission
  • Hypersensitivity to acetylcysteine.
  • Pregnancy

Treatment and study plan

mucomyst

Drug

sodium chloride (saline)

Drug

Primary outcomes

  1. prevention of pulmonary mucus obstruction

Secondary outcomes

  1. days of mechanical ventilation

Sponsors and collaborators

Lead sponsor

The University of Texas Health Science Center at San Antonio

Other

Registry information

Official study title

Comparison of Different Mucoactive Agents for the Care of the Intubated Patient in a Surgical Trauma Intensive Care Unit: A Randomized, Double Blind, Controlled Trial

Important dates

Study start
2005
Study completion
2007
First posted
Aug 18, 2005
Registry last updated
Jun 23, 2009

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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