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NCT Number: NCT06278987

Comparison of Cryoablation of Pericapsular Nerve Group (PENG) to Fascia Iliaca Catheter in Patients With a Hip Fracture

The purpose of this study is to determine if patients with hip fractures who undergo cryoablation of the PENG have improved pain control 30 days from surgery when compared to those who have a fascia iliaca catheter.

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Key information

Conditions

Hip Fractures Femoral Fractures Fractures, Bone Hip Injuries Leg Injuries Wounds and Injuries

Age range

18 year–85 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

University of Minnesota

Minneapolis, Minnesota, 55414, United States

Location status: Recruiting

Location contact

Candace Nelson

CONTACT

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients undergoing hip fracture repair aged 18-85.

Exclusion criteria

  • Patients who have an exclusion to regional anesthesia.
  • Patients who are pregnant assessed via self-report or pregnancy test if they have taken one.
  • Non-English speakers
  • Patients who already had their fracture repaired"

Treatment and study plan

PENG block and cryoablation

Drug

will receive an ultrasound guided PENG block with 20 mL of 0.5% bupivacaine followed by cryoablation of the PENG nerves.

Fascia iliaca compartment block

Drug

will receive an ultrasound guided fascia iliaca compartment catheter with initial bolus of 20 mL of 0.5% bupivacaine followed by infusion of 0.2% ropivacaine at 10 mL per hour

Primary outcomes

  1. Maximum pain score on Post-operative day 30

    Time frame: 30 days post surgery

    Maximum pain score on day 30 post surgery. Pain Scale is 0-10 with 0 meaning no pain (better outcome) and 10 meaning worst pain imaginable (worse outcome).

  2. Opioid use

    Time frame: day 0, 1, 2, 3, 4, 5, 6, 7 post surgery

    Opioid use and Functional Pain scores on POD 0, 1, 2, 3, 4, 5, 6, 7 - measured in milligrams morphine equivalents

  3. functional pain scores

    Time frame: day 0, 1, 2, 3, 4, 5, 6, 7 post surgery post surgery

    Functional Pain Score on Post Operative Day 0, 1, 2, 3, 4, 5, 6, 7 - measured with Pain Scale 0-10 with 0 meaning no pain (better outcome) and 10 meaning worst pain imaginable (worse outcome)

  4. number of patients using opioids

    Time frame: 30 days post surgery

    measured in number of patients

  5. Length of Hospital Stay

    Time frame: 30 days post surgery

    measured in number of days

  6. Time to first ambulation

    Time frame: 30 days post surgery

    measured in Days:Hours:Minutes post operation

  7. Number of patients returned home by Post Operative Day 30

    Time frame: 30 days post surgery

    measured in number of patients

Study contacts

Contact information is provided by the study sponsor or research team.

Candace Nelson

CONTACT

[email protected]

Sponsors and collaborators

Lead sponsor

University of Minnesota

Other

Registry information

Important dates

Study start
2024
Primary completion
2026
Study completion
2027
First posted
Feb 26, 2024
Registry last updated
Nov 25, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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