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NCT Number: NCT06617559

Comparison of Autologous Quadriceps and Hamstring Tendon Grafts in Anterior Cruciate Ligament Reconstruction

With the recent technological advancements, the use of the quadriceps tendon with an all-inside technique has come to the forefront, and large-scale research has focused especially on quadriceps tendon grafts. Clinical study results have reported that the outcomes are similar to those of patellar tendon grafts and either equivalent or superior to hamstring tendon grafts.

The aim of this study is the prospective comparison of the clinical and radiological outcomes of patients who underwent anterior cruciate ligament (ACL) reconstruction with autologous hamstring and quadriceps tendon grafts.

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Key information

Conditions

Anterior Cruciate Ligament Injuries Athletic Injuries Knee Injuries Leg Injuries Tendon Graft; Complications Wounds and Injuries

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Acibadem Fulya Hospital

Istanbul, 34394, Turkey (Türkiye)

Location status: Recruiting

Location contact

Muzaffer Agir

CONTACT

[email protected]

+905543060011

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Elite athletes
  • Amateur athletes
  • Anterior cruciate ligament injury

Exclusion criteria

  • Revision surgery
  • Another ligament injury ( medial collateral ligament, lateral collateral ligament, etc.. )
  • > Grade-2 cartilage injury
  • Having previously undergone surgery on the same knee
  • < 18 years age

Treatment and study plan

Anterior Cruciate Ligament Reconstruction with Quadriceps Autograft

Procedure

The investigators will perform all-inside anterior cruciate ligament reconstruction using only the tendon portion of the quadriceps tendon (without bone fragments) in this group.

Anterior Cruciate Ligament Reconstruction with Hamstring Autograft

Procedure

The investigators will perform all-inside anterior cruciate ligament reconstruction using the hamstring tendon as a graft in this group.

Primary outcomes

  1. Autograft Maturation

    Time frame: 12 months

    Comparison of different autografts maturation on MRI images. The signal-to-noise quotient formula will be used to assess graft maturation. According to the method described by Chan and Yau, the difference between the signals of the ACL graft and the quadriceps tendon will be used to evaluate maturation by relating it to the background signal.

  2. Stability of Knee

    Time frame: 9 months

    Pivot shift test

  3. Stability of Knee

    Time frame: 9 months

    laxity measuring with KT-1000 device

  4. Stability of Knee

    Time frame: 9 months

    Lachman test

Secondary outcomes

  1. Range of Motion

    Time frame: 6 months

    Measurement of knee flexion and extension degrees with a goniometer.

  2. Muscle Strength

    Time frame: 9 months

    Measurement of quadriceps and hamstring muscle strength with Cybex test

Study contacts

Contact information is provided by the study sponsor or research team.

Muzaffer Agir, MD

CONTACT

[email protected]

+905543060011

Sponsors and collaborators

Lead sponsor

Muzaffer Agir

Other

Collaborators

  • Acibadem University

Registry information

Official study title

A Prospective Comparison of Clinical and Radiological Maturation Outcomes of Autologous Quadriceps and Hamstring Tendon Grafts in Anterior Cruciate Ligament Reconstruction

Important dates

Study start
2024
Primary completion
2025
Study completion
2026
First posted
Sep 27, 2024
Registry last updated
Sep 27, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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