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Completed

NCT Number: NCT06928402

Comparison of Airway Ultrasound Measurements

Evaluating the success of measurements taken with ultrasound airway imaging in predicting difficult intubation by comparing conventional parameters in terms of difficult intubation and the proportion of patients encountered during intubation and characterised as difficult.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Ankara Ataturk Sanatorium Research and Training Hospital

Ankara, Turkey (Türkiye)

About this study

Clinical screening tests, which have long been routinely used for airway assessment, do not have sufficient sensitivity and specificity to detect difficult laryngoscopy. The Cormack-Lehane laryngoscopy classification, which can be assessed during direct laryngoscopy, is an invasive procedure and is not suitable for routine preoperative airway assessment. Preoperative airway assessment using ultrasound can help to predict a difficult laryngoscopy and/or difficult intubation and is growing in popularity as a non-invasive diagnostic tool. Several recent studies have emphasised the importance of various ultrasound-mediated airway measurements in predicting difficult intubation, and have shown that measurements with different parameters and data obtained by ratioing some measurements to each other may have an important role. However, the parameters obtained by ultrasound-mediated airway measurement can help determine airway anatomy and guide airway interventions with dynamic real-time images.

In this study, investigators used hyoid bone visibility obtained through preoperative ultrasound evaluation of the upper airway, followed by measurements of the skin-hyoid distance, skin-cricothyroid membrane distance and length, and hyomental distance in two different positions-neutral and extension. The ratios of these measurements were analyzed to predict difficult intubation. Traditional parameters commonly used as indicators of difficult ventilation and/or intubation, such as the Mallampati-Samsoon classification, upper lip bite test, thyromental distance, sternomental distance, neck circumference, maximum mouth opening, Wilson difficult intubation score, and Han ventilation scale, were also included in the study.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients to be operated with endotracheal intubation under elective conditions
  • Voluntary patients whose informed consent was obtained,
  • Patients older than 18 years
  • Patients evaluated in the 1-2-3 category of the American Society of Anaesthesiologist (ASA)

Exclusion criteria

  • Patients with a history of difficult intubation
  • Pregnant patients
  • Patients with a history of surgery in the head and neck region
  • Patients with a history of trauma or tumour in the head and neck region
  • Presence of a syndrome that will cause difficult intubation
  • Uncooperative patients,
  • Patients with missing data

Treatment and study plan

No intervention

Other

no interventions will be performed by the research team

Primary outcomes

  1. Ratio of ultrasound-derived parameters with conventional parameters

    Time frame: 1 hour peroperatively

    ultrasound derived parameters: hyoid bone visibility, skin-hyoid distance, skin-hyoid distance, skin-crricothyroid membrane distance, cricothyroid membrane length and hyomental distance measured in neutral and extension and the ratio of these values.

    Conventional parameters: thyromental distance, sternomental distance, upper lip bite test, head-neck movement, presence of retrognathia, neck circumference, maximum mouth opening, Wilson difficult intubation score, Han scale and Mallampati score

Secondary outcomes

  1. Incidence of difficult intubation

    Time frame: 1 hour peroperatively

    Defined as ≥3 intubation attempts by an experienced anesthesiologist, use of adjunctive devices (e.g., stylet, LMA, video laryngoscope), or duration >10 minutes.

  2. Incidence of difficult ventilation

    Time frame: 1 hour preoperatively

    Grade 3 and 4 for Han scale.( Difficulty of mask ventilation (DMV) has been classified using the Han scale.)

Sponsors and collaborators

Lead sponsor

Ankara Ataturk Sanatorium Training and Research Hospital

Other Gov

Registry information

Official study title

Comparison of Airway Ultrasound Measurements With Conventional Parameters in Predicting Difficult Intubation

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Apr 15, 2025
Registry last updated
Sep 19, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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