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NCT Number: NCT07586670

Comparison of 90° and 120° Arm Positions in Costoclavicular Block

The costoclavicular approach of the infraclavicular brachial plexus block is widely used for upper extremity surgeries due to its reliable anatomy and high success rates. Patient positioning, particularly the degree of arm abduction, may influence the spread of local anesthetic and the characteristics of the block. However, the optimal arm abduction angle during this procedure remains unclear.

This prospective randomized controlled trial aims to investigate the effect of two different arm abduction angles (90° and 120°) on block onset time and block success in patients undergoing hand, wrist, and forearm surgery under ultrasound-guided costoclavicular brachial plexus block.

Patients will be randomly assigned to one of two groups according to the degree of arm abduction. The primary outcome is block onset time. Secondary outcomes include block success, sensory and motor block characteristics, perfusion index changes, hemodynamic parameters, readiness for surgery at 15 and 20 minutes, block performance time, need for additional anesthesia, postoperative neurological evaluation at 4 and 24 hours, complications, and patient satisfaction.

The findings of this study are expected to provide evidence on optimal patient positioning to improve the effectiveness and reliability of ultrasound-guided costoclavicular brachial plexus block.

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Key information

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

About this study

The costoclavicular approach is a recently described infraclavicular technique for brachial plexus block that provides reliable anesthesia for upper extremity surgeries. Due to the compact arrangement of the cords in the costoclavicular space, this technique has gained popularity for its high success rates and consistent anatomy. However, procedural factors such as patient positioning may influence the distribution of local anesthetic and the effectiveness of the block.

Arm abduction is known to alter the anatomical relationships within the infraclavicular region, potentially affecting needle visualization, spread of local anesthetic, and block characteristics. Despite its clinical relevance, there is limited evidence regarding the optimal degree of arm abduction during ultrasound-guided costoclavicular brachial plexus block.

This prospective randomized controlled study aims to compare two different arm abduction angles 90° and 120° in patients undergoing elective hand, wrist, and forearm surgery. After obtaining written informed consent, eligible patients will be randomly assigned into two groups according to the degree of arm abduction.

All procedures will be performed under ultrasound guidance using a standardized technique. The local anesthetic will be administered in the costoclavicular space, and block characteristics will be assessed systematically. The primary outcome is block onset time, defined as the time from completion of local anesthetic injection to the achievement of adequate sensory block for surgery.

Secondary outcomes include block success, sensory and motor block scores, perfusion index measurements, hemodynamic parameters, readiness for surgery at 15 and 20 minutes, block performance time, need for additional anesthesia or conversion to general anesthesia, early complications, postoperative neurological evaluation at 4 and 24 hours, and patient satisfaction assessed using a Likert scale.

The results of this study are expected to provide valuable evidence regarding optimal patient positioning and contribute to improving the clinical effectiveness and reliability of ultrasound-guided costoclavicular brachial plexus block.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients aged between 18 and 80 years.
  • Patients scheduled for elective upper extremity surgery (hand, wrist, forearm).
  • Patients classified as ASA I-III.
  • Patients who provide informed consent after being informed about the study.

Exclusion criteria

  • History of previous surgery, scar tissue, tumor, or trauma that may alter brachial plexus anatomy.
  • Presence of infection, hematoma, severe edema, burn, or open wound at the block application site.
  • Known allergy to local anesthetics or other medications used in the study.
  • Coagulopathy, use of anticoagulants, or platelet count < 100,000/mm³.
  • History of peripheral neuropathy, neurological deficit, cervical radiculopathy, or CRPS.
  • Pregnancy or breastfeeding.
  • Patients with BMI < 18 kg/m².
  • Patients with BMI > 35 kg/m².
  • Severe cardiac, pulmonary, renal, or hepatic failure.
  • Mental retardation, communication difficulties, or lack of cooperation.
  • Deformity, amputation, or large mass in the surgical extremity that may interfere with sensorimotor assessment.
  • Preoperative significant sensory loss, motor weakness, or signs of neurological disease.
  • Severe anemia (Hb < 9 g/dL) or polycythemia (Hb > 18 g/dL).
  • Psychiatric disorders, substance abuse, or any condition that may interfere with study compliance.

Treatment and study plan

Costoclavicular brachial plexus block

Procedure

Ultra-sound Guided costoclavicular brachial plexus block performed for upper extremity surgery using a standard local anesthetic technique

Primary outcomes

  1. Block Onset Time

    Time frame: Up to 30 minutes after block performance

    Time from completion of local anesthetic injection to achievement of adequate sensory block sufficient for surgery, assessed by pinprick test.

Secondary outcomes

  1. Block Success

    Time frame: İntraoperative period

    Successful completion of surgery without the need for additional anesthesia.

  2. Sensory Block Score

    Time frame: Baseline and at 5-minute intervals up to 20 minutes after block performance.

    Sensory block was assessed using a 3-point pinprick scale ( 0= normal sensation, 1= loss of pinprick sensation, 2= complete sensory block).

  3. Motor Block Score

    Time frame: Baseline and at 5-minute intervals up to 30 minutes after block performance.

    Motor block was assessed using a 3-point motor scale (0= normal motor function, 1= reduced motor strength, 20 complete motor block).

  4. Perfusion Index

    Time frame: Baseline and at 5,10,15 and 20 minutes after block performance.

    Perfusion index values measured using a Masimo pulse oximeter probe placed on the blocked upper extremity.

  5. Readiness for Surgery

    Time frame: 15 minutes after block

    Proportion of patients ready for surgery at 15 and 20 minutes.

  6. Readiness for Surgery

    Time frame: 20 minutes after block

    Proportion of patients ready for surgery at 15 and 20 minutes

  7. Block Performance Time

    Time frame: During procedure ( min )

    Time required to perform the block.

  8. Need for Additional Anesthesia

    Time frame: Intraoperative period

    Requirement for supplemental anesthesia or conversion to general anesthesia.

  9. Complications

    Time frame: Up to 24 hours

    Early complications related to block

  10. Postoperative Sensory and Motor Function Assessment

    Time frame: 4 hours after surgery

    Postoperative neurological evaluation including sensory and motor function examination of the blocked upper extremity to assess for neurological complications.

  11. Postoperative Sensory and Motor Function Assessment

    Time frame: 24 hours after surgery

    Postoperative neurological evaluation including sensory and motor function examination of the blocked upper extremity to assess for neurological complications.

  12. Patient Satisfaction

    Time frame: At the end of the surgery and 24 hours postoperatively

    Patient satisfaction assessed using a 5-point Likert scale, where 1 indicates very dissatisfied and 5 indicates very satisfied.

  13. Hemodynamic Parametres

    Time frame: Baseline and at 5,10,15 and 20minutes after block performance

    Heart rate

  14. Systolic Blood Pressure

    Time frame: Baseline and at 5,10,15 and 20 minutes after block performance.

    Systolic blood pressure values measured during and after block performance.

  15. Diastolic Blood Pressure

    Time frame: Baseline and at 5,10,15 and 20 minutes after block performance.

    Diastolic blood pressure values measured during and after block performance.

  16. Mean Arterial Pressure

    Time frame: Baseline and at 5,10,15 and 20 minutes after block performance.

    Mean arterial pressure values measured during and after block performance.

Study contacts

Contact information is provided by the study sponsor or research team.

Algan TURGUT ÇARSANCAKLI, M.D.

CONTACT

[email protected]

+90 532 486 52 69

Reyhan POLAT, Professor

CONTACT

[email protected]

+90 532 673 43 10

Sponsors and collaborators

Lead sponsor

Ankara Etlik City Hospital

Other Gov

Registry information

Official study title

Effect of Arm Abduction Degree ( 90° vs. 120° ) on Block Onset Time and Block Success in Costoclavicular Brachial Plexus Block in Patients Undergoing Hand, Wrist and Forearm Surgery: A Prospective Randomized Controlled Trial

Acronym: COSTO-RCT

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
May 14, 2026
Registry last updated
Jun 9, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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