Ankara Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Ankara, Turkey (Türkiye)
NCT Number: NCT06360510
The aim of the study is to compare the effectiveness of ultrasound-guided betamethasone and 5% dextrose injection, which is routinely applied in clinical practice, in patients with mild and moderate carpal tunnel syndrome (CTS).
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Notify Me18 year–75 year
All sexes
Observational
Ankara, Turkey (Türkiye)
It is planned as an observational, single-center clinical study.A total of 28 patients diagnosed with mild-moderate carpal tunnel syndrome who meet the inclusion criteria will be included in the study.Patients who had been experiencing trigger finger symptoms for at least three month and who presented to the Gaziler Physical Medicine and Rehabilitation Training and Research Hospital, affiliated with the Health Sciences University Faculty of Medicine.
Patients will be divided into two groups. One group will receive 5% dextrose, the other group will receive 1 session of local injection by mixing Celeston chronodose [1ml/3 mg betamethasone acetate+3,947 mg betamethasone disodium phosphate (equivalent to 3 mg betamethasone)] and 1 ml 2% prilocaine.
Evaluations will be made before injection, at weeks 4 and 12.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
hydrodissection with %5 dextrose
perineural betamethasone injection
Time frame: three months
The Numeric Rating Scale (NRS) is a simple and widely used tool for assessing pain intensity. Patients are asked to rate their pain on a scale from 0 to 10, where: 0 = No pain
1-3 = Mild pain
4-6 = Moderate pain
7-9 = Severe pain
10 = Worst pain imaginable
The patient selects the number that best represents their pain at last one week
Time frame: three months
The Boston Carpal Tunnel Syndrome Questionnaire (BCTQ) is a disease-specific, patient-reported outcome measure used to assess symptom severity and functional status.1. Symptom Severity Scale (SSS)
Contains 11 items
Evaluates pain, numbness, tingling, weakness, nocturnal symptoms, and symptom frequency
Each item is scored on a 5-point Likert scale (1 = no symptoms, 5 = very severe symptoms)
Contains 8 items
Assesses difficulty in performing daily activities such as writing, buttoning clothes, holding a book, gripping a telephone, opening jars, and carrying grocery bags
Each item is scored from 1 (no difficulty) to 5 (cannot perform the activity)
Time frame: three months
Median nerve cross-sectional area (CSA) refers to the measured area of the median nerve in a transverse (axial) plane, most commonly assessed using high-resolution ultrasonography.CSA measurements were performed using ultrasound at the scaphoid - pisiform bone level in the wrist, with results recorded in mm². To minimize measurement error, each measurement was performed three times, and the average of the three measurements was used for analysis.
Time frame: three months
Tinel test positivity refers to the reproduction of distal paresthesia in the distribution of a nerve following percussion over the nerve at a suspected site of compression.
Definition of Positivity
The test is considered positive when tapping elicits:
Tingling
"Pins and needles" sensation (paresthesia)
Electric shock-like sensation
radiating into the median nerve distribution (thumb, index finger, middle finger, and radial half of the ring finger).
Time frame: three months
The Phalen test is performed by asking the patient to fully flex both wrists and maintain this position for approximately 60 seconds. This maneuver increases pressure within the carpal tunnel.
Definition of Positivity
The test is considered positive when the patient experiences:
Numbness
Tingling (paresthesia)
Burning sensation
Pain
in the distribution of the median nerve (thumb, index finger, middle finger, and radial half of the ring finger) during the maneuver.
Time frame: three months
The Duruöz Hand Index (DHI) is a patient-reported outcome measure developed to assess functional disability of the hand.Structure
The questionnaire consists of 18 items.
It assesses hand-related functional activities such as:
Turning a key
Buttoning clothes
Opening jars
Carrying objects
Using kitchen utensils
Scoring
Each item is scored on a 6-point Likert scale:
0 = Without difficulty
The total score ranges from 0 to 90.
Higher scores indicate greater functional impairment.
Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Other
Comparison of the Effectiveness of Ultrasound-guided 5% Dextrose and Betamethasone Injections in Patients With Carpal Tunnel Syndrome.
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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