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OpenTrials
Completed

NCT Number: NCT04865614

Comparison Between Inhalation and Intravenous Induction of Anaesthesia During Interventional Mitral Valve Repair

The induction of anaesthesia is one of the most critical situations for high-risk-patients undergoing interventions surgery. For several reasons, it is crucial to maintain adequate blood pressure and cardiac output during this phase.

This retrospective cohort study aims to find out if the choice of the induction agent has a major impact on blood pressure and the use of catecholamines during the induction and the interventional procedure in patients undergoing interventional mitral valve repair.

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Key information

Conditions

Blood Pressure Cardiovascular Diseases Hypotension Hypotension Drug-Induced Vascular Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Anästhesiologische Klinik (Universitätsklinikum Heidelberg)

Heidelberg, Baden-Würtemberg, 69120, Germany

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients undergoing elective interventional mitral valve repair
  • Sevoflurane or etomidate have been used for induction of anesthesia

Exclusion criteria

  • Pregnancy

Treatment and study plan

Etomidate

Drug

Use of etomidate

Sevoflurane

Drug

Use of sevoflurane

Primary outcomes

  1. Post-induction hypotension

    Time frame: First 20 minutes after induction of anaesthesia

    Hypotension in the first 20 minutes after induction of anesthesia

Secondary outcomes

  1. Use of catecholamines after induction during the first 20 minutes after inductionafter induction

    Time frame: First 20 minutes after induction

    Use of catecholamines during the first 20 minutes after induction of anaesthesia

  2. Use of catecholamines

    Time frame: Length of procedure (Approximately 60 to 90 minutes in average)

    Use of catecholamines during the procedure

Sponsors and collaborators

Lead sponsor

Heidelberg University

Other

Collaborators

  • University Hospital, Essen

Registry information

Acronym: COMPETENT

Important dates

Study start
2019
Primary completion
2020
Study completion
2020
First posted
Apr 29, 2021
Registry last updated
Oct 26, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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