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NCT Number: NCT07724743

Comparative Evaluation of Functional and Aesthetic Outcomes of Box and Mini-Wing Genioplasty Techniques

This retrospective cohort study aims to compare the effects of Mini Wing and Box genioplasty performed in conjunction with bimaxillary orthognathic surgery on upper airway area and soft tissue profile in adult patients with skeletal Class II dentofacial deformity. Preoperative and postoperative radiographic measurements will be evaluated to determine changes in upper airway area, mentolabial angle, and submental angle. The study also aims to assess whether either genioplasty technique provides superior postoperative functional and esthetic outcomes.

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Key information

Conditions

Class II Malocclusion Congenital Abnormalities Congenital, Hereditary, and Neonatal Diseases and Abnormalities Craniofacial Abnormalities Dentofacial Deformities Jaw Abnormalities Jaw Diseases Malocclusion Malocclusion, Angle Class II Mandibular Diseases Maxillofacial Abnormalities Musculoskeletal Abnormalities Musculoskeletal Diseases Overbite Retrognathia Stomatognathic Diseases Stomatognathic System Abnormalities Tooth Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Istanbul Medipol University Hospital

Bağcılar, Istanbul, 34214, Turkey (Türkiye)

About this study

Skeletal Class II dentofacial deformity is commonly treated with bimaxillary orthognathic surgery combined with genioplasty to improve facial harmony and functional outcomes. Among the available genioplasty techniques, Mini Wing and Box genioplasty differ in their osteotomy design and the direction of chin advancement, which may influence postoperative soft tissue profile and upper airway morphology.

This retrospective cohort study includes adult patients who underwent bimaxillary orthognathic surgery with either Mini Wing or Box genioplasty at Istanbul Medipol University between 2019 and 2025. Patients meeting the predefined inclusion and exclusion criteria will be identified through hospital records. Preoperative and postoperative cone-beam computed tomography (CBCT) images will be analyzed to evaluate changes in upper airway area, mentolabial angle, and submental angle.

Demographic characteristics and baseline measurements will be compared between groups to ensure similarity before surgery. Postoperative changes within each group and differences between the two surgical techniques will be statistically analyzed. The findings are expected to provide evidence regarding the effects of Mini Wing and Box genioplasty on upper airway dimensions and soft tissue profile, thereby supporting surgical planning and technique selection in patients with skeletal Class II deformity.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adults aged 18 years or older.
  • Diagnosis of skeletal Class II dentofacial deformity.
  • Underwent bimaxillary orthognathic surgery combined with either Mini Wing or Box genioplasty.
  • Available preoperative and postoperative CBCT images obtained 6 months after surgery.
  • Complete clinical and radiographic records.

Exclusion criteria

  • Previous orthognathic or genioplasty surgery.
  • Craniofacial syndromes or congenital craniofacial anomalies.
  • History of facial trauma affecting craniofacial morphology.
  • Incomplete clinical records or missing CBCT data.
  • Poor-quality CBCT images unsuitable for analysis.

Treatment and study plan

Mini Wing Genioplasty

Procedure

Mini Wing genioplasty performed in conjunction with bimaxillary orthognathic surgery for correction of skeletal Class II dentofacial deformity.

Box Genioplasty

Procedure

Box genioplasty performed in conjunction with bimaxillary orthognathic surgery for correction of skeletal Class II dentofacial deformity.

Primary outcomes

  1. Change in Upper Airway Area

    Time frame: Preoperative and 6 months after surgery

    Change in upper airway area measured on cone-beam computed tomography (CBCT) images obtained before surgery and 6 months after surgery.

Secondary outcomes

  1. Change in Mentolabial Angle

    Time frame: Preoperative and 6 months after surgery

    Change in the mentolabial angle measured on CBCT images before surgery and 6 months after surgery.

  2. Change in Submental Angle

    Time frame: Preoperative and 6 months after surgery

    Change in the submental angle measured on CBCT images before surgery and 6 months after surgery.

Sponsors and collaborators

Lead sponsor

Istanbul Medipol University Hospital

Other

Registry information

Acronym: MWBOX

Important dates

Study start
2019
Primary completion
2026
Study completion
2026
First posted
Jul 24, 2026
Registry last updated
Jul 24, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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