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NCT Number: NCT05812053

Comparative Evaluation of Eggshell Powder in Primary Teeth Pulpotomy

To assess & compare clinical & radiographic effects of Eggshell Powder, Biodentine and MTA as pulpotomy agents in primary teeth.

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Key information

Conditions

Pulpitis Reversible Dental Pulp Diseases Dental Pulp Exposure Pulp Exposure, Dental Stomatognathic Diseases Tooth Diseases

Age range

4 year–7 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Tanta University

Tanta, Gharbia Governorate, 6624033, Egypt

Location status: Recruiting

Location contact

Shaimaa eldesouky, PhD

CONTACT

[email protected]

+201008994242

About this study

Pulpotomy is the most widely accepted technique for treating primary teeth with deep carious lesion, pulp exposure during the operatory process or after a traumatic pulp exposure. Mineral trioxide aggregate (MTA) is one such material that has shown tremendous potential for regeneration. Biodentine™ (hydraulic silicate cement) is a novel dental material with high mechanical characteristics as well as superior biocompatibility and bioactive behaviour. Nowadays, chicken eggshell powder (CESP) (a natural calcium-rich source) is achieving wide acceptance in the medical and dental fields. To date, there is insufficient evidence to properly evaluate Eggshell Powder as a pulpotomy agent in primary teeth; thus, the current study aimed to assess and compare clinical and radiographical success of Eggshell Powder, Biodentine and MTA as pulpotomy agents in primary teeth.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Restorable primary molars with deep carious lesions.
  • Absence of gingival swelling or sinus tract.
  • Absence of spontaneous pain
  • Absence of pain on percussion.
  • Absence of discontinuity of lamina dura
  • Absence of internal root resorption.
  • Absence of external root resorption.
  • Absence of inter-radicular or periapical bone destruction (radiolucency).

Exclusion criteria

  • presence of spontaneous pain
  • presence of gingival swelling or sinus tract
  • presence of internal or external root resorption
  • pain on percussion.

Treatment and study plan

Pulpotomy

Procedure

Teeth will be anesthetized then Rubber dam and high suction will be used in pulpotomy procedure. Cavity outline was performed by sterile #330 high speed bur using water spray. Caries was removed by large spoon excavator. When pulpal exposure occurred, the roof of pulp chamber removed by low speed round bur. Haemostasis was obtained by applying pressure with moist cotton pellet with saline. Then the test materials was applied. after that, pulp stumps of all molars in each group will be dressed using Intermediate restorative material then the tooth will be restored with a preformed stainless steel crown

cone beam computed tomography (CBCT) assessment

Radiation

a post-operative CBCT image will be taken immediately after completing the procedure with fixed exposure parameters (120 Kv, 5mA, and 0.125mm voxel size) using the smallest field of view (8D, 8Hcm) also, after 12 months follow-up periods.

Primary outcomes

  1. absence of pain

    Time frame: up to 12 months

    Measuring Method: Verbal Question to Patient /Parents Measuring Unite: score 0 for absence of pain and score 1 for presence of pain

  2. absence of fistula

    Time frame: up to 12 months

    Measuring Method: Visual examination by operator Measuring Unite: score 0 for absence of swelling and score 1 for presence of swelling

  3. Tenderness to percussion

    Time frame: Up to 12 month

    Measuring Method: Percussion test Measuring Unite: Binary (+/-)

  4. Furcation radiolucency

    Time frame: 6 months

    Measuring Method: cone beam computed tomography (CBCT) for assessment of radio-density of bone at the furcation area Measuring Unite: Binary (+/-)

  5. Furcation radiolucency

    Time frame: 12 months

    Measuring Method: cone beam computed tomography (CBCT) for assessment of radio-density of bone at the furcation area Measuring Unite: Binary (+/-)

Study contacts

Contact information is provided by the study sponsor or research team.

shaimaa eldesouky, lecturer

CONTACT

[email protected]

+201008994242 ext. tanta

Sponsors and collaborators

Lead sponsor

Tanta University

Other

Registry information

Official study title

Comparative Evaluation of Eggshell Powder Versus Biodentine in Primary Teeth Pulpotomy: Clinical And Radiographic Study

Important dates

Study start
2023
Primary completion
2026
Study completion
2026
First posted
Apr 13, 2023
Registry last updated
Dec 26, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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