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NCT Number: NCT06686212

Comparative Effects of Sensory Re-education and Neural Mobilization in CTS Patients

The aim of study is to compare the effects of sensory re-education and neural mobilization in CTS patients.

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Key information

Conditions

Carpal Tunnel Syndrome (CTS) Carpal Tunnel Syndrome Cumulative Trauma Disorders Median Neuropathy Mononeuropathies Nerve Compression Syndromes Nervous System Diseases Neuromuscular Diseases Peripheral Nervous System Diseases Sprains and Strains Wounds and Injuries

Age range

20 year–50 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

About this study

This study will be randomized clinical trial that will be conducted at Services Hospital Lahore and Government Teaching Hospital Shahdara. In this study 48 participants with CTS will be included as per sample size calculation through non-probability convenience sampling technique. Participants that achieve the required standards of inclusion and exclusion criteria will be randomly allocated using online randomization tool into two groups. Group A will receive Sensory Re-education therapy, strengthening exercises and Kinesio taping for 60 minutes, Group B will be given neural mobilization techniques, strengthening exercises and Kinesio taping for 60 minutes with short rest intervals. Both treatments will be given 3 days per week for 12 weeks.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients of both genders age 20-50 years with mild and moderate carpal tunnel syndrome.
  • Patients having positive score on CTS specific test (Phalen's test and Tinel's test).
  • Patients with pain, paresthesia and hyperesthesia at the course of median nerve.
  • Patients that are clinically diagnosed with carpal tunnel syndrome by physician. Patients having BMI >25 (kg/m2).

Exclusion criteria

  • Patients with polyneuropathies.
  • Patients with carpal tunnel syndrome due to any systemic illness (diabetes mellitus, thyroid diseases and R.A).

Patients having cervical radiculopathy.

Patients with history of wrist fracture.

Patients getting steroid injections and after CTS surgery.

Obese and pregnant female with carpal tunnel syndrome.

Patients with any cognitive or neurological problems are excluded from study.

Treatment and study plan

Sensory re-education+ strengthening exercises+ kinesio taping

Other

Sensory re-education. Splinting: as constant maintained touch with wrist holding in neutral position for 15 minutes.

Topical anesthesia spray on affected area for 10 minutes. Massage: apply massage over sensitive areas with same speed and pressure, then the light pressure with cotton, velvet, terry cloth, polyester and wool over sensitive area for 10 minutes.

PNF using upper extremity (D2) pattern including shoulder extension, adduction, internal rotation, wrist and fingers flexed and wrist ulnar deviated. 10-15 repetitions for 5 minutes.

Strengthening exercises: wrist flexion and extension, supination and pronation, opposition, gripping, ball squeeze and fingers pinching against resistance. 10-15 repetitions of each exercise for 20 minutes.

Kinesio taping: Taping will be applied twice a week for 12 weeks.

Neural mobilization+ Strengthening exercises+ Kinesio taping.

Other

The median nerve is mobilized through wrist flexion and extension with elbow straight and palm facing up.

Wrist flexion and extension with elbow flexed to 90 degrees with palm facing up 10-15 repetitions.

Wrist flexors stretch with extended arm and palm facing down 10-15 repetitions. Straight fist: hold your hand up with fingers straight. Full fist: bend your fingers to form a full fist. Median nerve stretch and wrist extension exercises for 30 minutes. Free the bird exercises, busy bee flexion shape of Z exercises and wall stretch exercise. (10-15 repetitions) for 10 minutes.

Strengthening exercises: wrist flexion and extension, supination and pronation, opposition, gripping, ball squeeze and fingers pinching against resistance. 10-15 repetitions each for 20 minutes.

Kinesio taping: The taping will be applied twice a week for 12 weeks.

Primary outcomes

  1. Numerical pain rating scale

    Time frame: 12th week

    The NPRS is use to capture the patient's level of pain. Patients are allowed to indicate the intensity of their current pain level using an 11-point scale, ranging from 0 (no pain) to 10 (worst pain imaginable).

  2. Boston Carpal Tunnel Questionnaire

    Time frame: 12th week

    A patient self-reported questionnaire includes 2 sub scales: The Symptom Severity Scale (SSS), which comprise 11 questions and uses a 5- point Likert scale; and the Functional Status Scale (FSS) having 8 items, which have to be evaluated for degree of difficulty on a 5-point Likert scale. Each scale generates a final score (sum of scores divided by number of items), which ranges from 1 to 5, with a higher score predicting greater disability.

  3. Hand Held Dynamometer

    Time frame: 12th week

    Hand grip strength is measured using a handheld dynamometer. Patients are asked to grip the dynamometer isometrically and advised to grip it as hard as they can. Readings will be taken in pounds lb. The average value of 3 trials is recorded.

  4. Pinch gauge meter

    Time frame: 12th week

    Tip pinch grip strength will be assessed using a manual dynamometer (pinch gauge meter). Participants asked to perform a maximal pinch grip by pressing the gauge between the tip of their thumb and index finger. The average of three trials will calculated and defined as the maximal tip pinch grip strength measured in kilograms.

Study contacts

Contact information is provided by the study sponsor or research team.

Iqra Liaqat, DPT

CONTACT

[email protected]

+92 348 4942418

Muhammad Kashif, PhD-PT

CONTACT

[email protected]

+92 333 3125303

Sponsors and collaborators

Lead sponsor

Riphah International University

Other

Registry information

Official study title

Comparative Effects of Sensory Re-education and Neural Mobilization in Carpal Tunnel Syndrome Patients

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Nov 13, 2024
Registry last updated
Nov 13, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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