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OpenTrials
Completed

NCT Number: NCT07622680

Comparative Effects of Mediterranean and DASH Diet on Hepatic Function

Participants were assigned into three groups Control group recieving general dietary guidelines, Mediterranean diet intervention group DASH dietary intervention group

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Key information

Age range

25 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of Lahore

Lahore, Pakistan

About this study

Written permission was taken from the ethical board for data collection. After taking informed consent from patients in written form, the researcher used self-administered questionnaire or Performa to gather data. NAFLD patients (both genders) of age 25 to 70 years were included.

  • Screening:

The participants eligible under inclusion criteria will be enrolled. The baseline data (weight, height, BMI, waist circumference, LFT's, Lipid profile, blood pressure). The target population between 25-70 years were selected.

  • Allocation:

The participants were assigned into three groups; control group was given dietary guidelines followed by medication; one group was given Mediterranean diet (T1) and other group was given DASH diet (T2) along with conventional therapy

  • Follow up:

The follow up of patient were conducted monthly, all laboratory test (LFT's, Lipid profile, blood pressure) were conducted on 1st and after 8th week. The baseline and post-test study were compared to test hypothesis.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adults (25-70 years) of both genders with BMI (above 25 kg/m2).
  • Fatty liver patients with mild to moderate values of Alanine Transaminase (ALT) level range from mild to moderate (30-100U/L)
  • Fatty liver patients having Aspartate Aminotransferase (AST) level range from mild to moderate (200-600 IU/L).
  • Fatty liver patients having Gamma-Glutamyl Transferase (GGT level range from mild to moderate(120-300 U/L) were included.

Exclusion criteria

  • Lactating and pregnant women were not included.
  • Patients who are using any kind of medicine.
  • Adults suffering from critical health conditions, including cancer.

Treatment and study plan

Dietary guidelines for fatty liver

Other

Dietary guidelines for managing fatty liver disease followed by medication for 2 months.

Mediterranean Diet

Other

Mediterranean diet plan consists of vegetables, whole grains, and fruit, extra virgin olive oil, nuts, seeds and legumes.

DASH diet

Other

DASH diet plan consists of antioxidant foods items i.e. fruits and vegetables lean meat and dairy products (low fat dairy products), nuts, grain.

Primary outcomes

  1. Body Mass Index

    Time frame: 60 days

    Body Mass Index (BMI) was computed by dividing weight in kilograms by the square of height in meters (kg/m2).

  2. Liver Function Test

    Time frame: 60 days

    The blood test was used to measure the serum concentrations of ALT, AST, and GGT. Following an overnight fast, 10 ml of venous blood was collected from participants both at baseline and post-intervention.

Sponsors and collaborators

Lead sponsor

University of Lahore

Other

Registry information

Official study title

Comparative Effects of Mediterranean and DASH Diet on Hepatic Function in Patients Suffering From NAFLD

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Jun 3, 2026
Registry last updated
Jun 3, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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