Raspberry Ketone Intake Upregulates Circulating FGF21 and Induces Energy Expenditure in Humans

To investigate the molecular mechanism of raspberry ketone on regulating obesity, the investigators studied the effect of raspberry ketone intake on FGF21 in plasma.

The age of the volunteers were 18-60 years old, both male and female, without diabetes, hypertension and other diseases.

After ingestion of raspberry ketone (500mg), 2ml of blood was collected at 0 hours, 3 hours and 6 hours , and the FGF21 content in plasma was measured using a commercial reagent kit.

In addition, the investigators also studied the effect of raspberry ketone intake on energy metabolism 0 hours, 0.5 hours, 3 hours and 6 hours after consuming raspberry ketone (500mg).

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Obesity Body Weight Diabetes Diabetes Mellitus Digestive System Diseases Endocrine System Diseases Fatty Liver Glucose Metabolism Disorders Liver Diseases Metabolic Diseases NAFLD (Nonalcoholic Fatty Liver Disease) Non-alcoholic Fatty Liver Disease Nutrition Disorders Nutritional and Metabolic Diseases Overnutrition Overweight Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

20 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Early Phase 1

Primary location

Nanchang University

Nanchang, Jiangxi, 330047, China

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

No drugs were taken before the human study

Exclusion criteria

Patients with hypertension

Treatment and study plan

Raspberry ketone

Dietary Supplement

Human consumed 500mg of raspberry ketone

Primary outcomes

Impact of raspberry ketone consumption on plasma FGF21 level

Time frame: Through study completion, an average of 1 year
Impact of raspberry ketone consumption on energy expenditure

Time frame: Through study completion, an average of 1 year

The oxygen consumption, heart rate, carbon dioxide production were measured

Sponsors and collaborators

Lead sponsor

Nanchang University

Other

Registry information

Official study title

The Effect of Raspberry Ketone Intake on Plasma FGF21 Levels

Important dates

Study start: 2024
Primary completion: 2024
Study completion: 2024
First posted: Nov 8, 2024
Registry last updated: Nov 8, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed