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NCT Number: NCT07578961

Combined Effects of Tactile Kinesthetic Stimulation With Neural Mobilization in Stroke Patients

Combined Effects of Tactile -kinesthetic stimulation with Neural mobilization on sensory and motor functions of upper limb in stroke patients

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This study is active but is not currently recruiting participants.

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Key information

Conditions

Stroke Brain Diseases Cardiovascular Diseases Central Nervous System Diseases Cerebrovascular Disorders Nervous System Diseases Vascular Diseases

Age range

45 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Lahore, Punjab Province, 54000, Pakistan

About this study

Stroke ranks among the primary causes of lasting disability, frequently leaving the upper limb weak, numb, or clumsy and thereby curtailing daily independence and overall well-being. Although multiple therapy regimens appear helpful, research to date Meestal tests each method alone, obscuring how paired sensory and motor targets might accelerate recovery. The present study investigates combined the effect of tactile-kinesthetic input with neural mobilization against standard care, hypothesizing that the blend will produce broader gains in sensation and movement.

This randomized clinical trial will be conducted at Ittefaq Hospital (Trust) Lahore and Gulab Devi Chest Hospital Lahore over duration of 11 months. The sample size will be (53) participants. Participants which meet the inclusion criteria will be taken through non-probability convenience sampling technique, which will further be randomized through lottery method. Group A (27) participants will be assigned to combined tactile kinesthetic stimulation plus neural mobilization and Group B (27)participants will be assigned to conventional therapy. Data will be collected through different assessment tools, including Fugyl-Meyer Assessment for motor function, Nottingham Sensory Assessment Scale (NAS) for sensory function. Pre-interventions assessments will be conducted for both groups. The effects of the interventions will be measured at pre-treatment and post-treatment of 6 weeks. Data analysis will be performed by using SPSS 26 software.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age between 45 - 65 years
  • Both gender Male and Female
  • Diagnosed with chronic stroke stated as occurring 6 month to 12 month .
  • Sensory impairment - loss of tactile and proprioception NSA ( < 7/12)
  • Motor impairment - lack in full strength and coordination ( Brunnstrom >3)
  • Scored 24 or higher on the Mini-Mental State Examination, indicating sufficient cognition to follow study instructions.

Exclusion criteria

  • Severe cognitive or communication difficulties that would prevent meaningful involvement in therapy or testing.
  • Comorbid conditions that impair upper-limb function, including arthritis, prior fractures, or similar disorders.
  • Neurological conditions other than stroke that could interfere with study outcomes
  • Engagement in any other rehabilitation program during the trial period.

Treatment and study plan

Tactile kinesthetic stimulation with neural mobilization

Other

The therapist rests a light touch on the limb, applying only the weight of fingertips Soft, gliding strokes travel across the skin, delivered with the very tips of the fingers Pressure remains steadily upon targeted patches of tissue without sliding away Measured, rhythmical strokes creep up and down the length of the arm or leg Smooth silk, rough jute, coarse sponge, and other materials are brushed over the skin in turn.Slowly glide the median nerve by extending wrist and fingers while gently abducting the shoulder.

kinesthetic therapy

Other

Median nerve mobilization: Slowly glide the median nerve by extending wrist and fingers while gently abducting the shoulder.

Ulnar nerve mobilization: Control elbow flexion and wrist extension while holding shoulder in slight abduction Radial nerve mobilization: Passively flex the wrist, pronate the forearm, and depress the shoulder to slide the radial nerve

Primary outcomes

  1. 1.Fugl-Meyer Assessment (FMA)

    Time frame: baseline with 4 week

    The Fugl-Meyer Assessment (FMA) was developed specifically for stroke survivors and is a performance-based tool that gauges sensorimotor deficits in people living with hemiplegia. The FMA examines five key areas: voluntary motor control, sensory perception, balance, passive joint range of motion, and joint-related pain. Within this battery, the motor section commands the most attention; it rates movement, coordination, and reflex activity in the arms and legs, yielding a ceiling score of 100 points (66 for the arm and 34 for the leg).

  2. 2.Nottingham Sensory Assessment (NSA)

    Time frame: baseline with 4 week

    The Nottingham Sensory Assessment, or NSA, provides clinicians with a standard method for mapping sensory loss after a stroke. Designed to examine both arms and legs, it centers on three core domains: touch, proprioception, and stereognosis. Within the protocol, practitioners test responses to light touch, gentle pressure, pinprick, temperature changes, and passive joint positioning. Because around half of all stroke survivors carry hidden somatosensory deficits that often impede movement, the tool is essential for early identification.

Sponsors and collaborators

Lead sponsor

Riphah International University

Other

Registry information

Official study title

Combined Effects of Tactile Kinesthetic Stimulation With Neural Mobilization on Sensory and Motor Functions of the Upper Limb in Stroke Patients

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
May 11, 2026
Registry last updated
May 11, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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