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NCT Number: NCT05994976

Collection of Samples From Subjects With Various Skin Conditions and Healthy Volunteers

The purpose of the study is to collect different samples for molecular characterization of inflammatory skin diseases.

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Key information

About this study

This study is being conducted to collect samples from subjects with various skin conditions as well as healthy volunteers. Collected samples may be used for different analyses including, but not limited to, biomarker and gene expression analyses.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

All subjects:

  • Subject is willing to participate and is capable of giving informed consent. Note: Consent must be obtained prior to any study-related procedures.
  • Subject must be willing to comply with all study procedures and must be available for the duration of the study.

Healthy volunteers:

  • Male or female subject aged 18 years or older, at the time of consent.
  • Subject is in good general health, according to the investigator's judgment.

Subjects with Acne:

  • Male or female subject aged 18 to 45 years old, inclusive, at the time of consent.

Subjects with AD:

  • Male or female subject aged 18 years or older, at the time of consent.
  • Subject has clinically confirmed diagnosis of active AD, according to Hanifin and Rajka criteria.

Subjects with CHE:

  • Male or female subject aged 18 years or older, at the time of consent.
  • Subject has at least a 6-month history of CHE before Screening (information obtained from medical chart or subject's physician, or directly from the subject).

Subjects with HS:

  • Male or female subject aged 18 years or older, at the time of consent.
  • Subject has a clinically confirmed diagnosis of active HS with a disease duration of ≥ 6 months before screening as determined by the investigator through subject interview and/or review of the medical history.

Subjects with PPP:

  • Male or female subject aged 18 years or older at the time of consent.
  • Subject has at least a 6-month history of PPP as defined by the presence of pustules on palms and/or soles, but without evidence of infection on palms and soles (information obtained from medical chart or subject's physician, or directly from the subject).

Subjects with psoriasis:

  • Male or female subject aged 18 years or older, at the time of consent.

Exclusion criteria

All subjects:

  • Subject is a female who is pregnant or who is planning to become pregnant during the study.
  • Subject has a history of skin disease or presence of skin condition that, in the opinion of the investigator, would interfere with the study assessments.

Treatment and study plan

Blood samples collection

Procedure

biomarkers and optional genetic analysis

Oral samples collection

Procedure

biomarkers analysis

Hair samples collection

Procedure

biomarkers analysis

Skin samples collection (skin tape strip and/or skin biopsy, and/or skin scraping)

Procedure

biomarkers analysis

Skin surface material samples

Procedure

biomarkers analysis

Drainage fluid samples collection

Procedure

biomarkers analysis

Stool samples collection

Procedure

biomarkers analysis

Primary outcomes

  1. Untargeted biomarker approach with gene expression profile of skin samples

    Time frame: Day 1

  2. Exploratory biomarker and gene expression analyses.

    Time frame: Day 1

Study contacts

Contact information is provided by the study sponsor or research team.

Julie Bedoucha, MSc

CONTACT

[email protected]

514-521-4285 ext. 253

Sponsors and collaborators

Lead sponsor

Innovaderm Research Inc.

Other

Registry information

Official study title

Collection of Samples From Subjects With Various Skin Conditions and Healthy Volunteers for Molecular Characterization of Inflammatory Skin Diseases

Important dates

Study start
2023
Primary completion
2028
Study completion
2028
First posted
Aug 16, 2023
Registry last updated
Mar 30, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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