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Completed

NCT Number: NCT01127711

Cohort of Swedish Men

The Cohort of Swedish Men began in 1997, when all men born between 1918 and 1952 and residing in two counties in central Sweden received a questionnaire including about 350 items concerning diet and other lifestyle factors. A second questionnaire was sent out in 2008-09.

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Key information

Conditions

Cancers Bone Diseases Bone Diseases, Metabolic Cardiovascular Diseases Cataract Digestive System Diseases Eye Diseases Fractures Fractures, Bone Gastrointestinal Diseases Lens Diseases Metabolic Diseases Musculoskeletal Diseases Neoplasms Nutritional and Metabolic Diseases Osteoporosis Wounds and Injuries

Age range

45 year–79 year

Sex eligibility

Male

Study type

Observational

About this study

The Cohort of Swedish Men was established in 1997, when all men born between 1918 and 1952 and residing in Västmanland and Örebro counties in central Sweden received a questionnaire concerning diet and other lifestyle factors. Of the 100,303 eligible men, 48,850 (49%) responded to the questionnaire. The questionnaire included items about diet, physical activity, medical history, and lifestyle factors such as cigarette smoking history and use of dietary supplements.

During 2008-09, the exposure information was updated and extended by sending out two new questionnaires - one questionnaire on health including several signs of symptoms, sleeping, social relations etc (2008) and one on diet, dietary supplement use, and lifestyle factors (2009). Majority of questions in the questionnaires have been validated.

Incident cases of cancer are ascertained by record linkages of the study population with the National Swedish Cancer Register and the Regional Cancer Registers. Cardiovascular and other diseases as well as surgeries and causes of death are identified by linkage to the National Inpatient and other registries at the Swedish Board of Health and Welfare. Ascertainment of cancer cases and other diseases is almost 100% complete. Dates of deaths are ascertained through the Swedish Death Register (100% complete), and information on date of moving out of the study area is obtained by linkage with the Swedish Population Register.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • All men born between 1918 and 1952, living in central Sweden

Exclusion criteria

  • None

Treatment and study plan

Primary outcomes

  1. Prostate cancer

    Time frame: 1997-2010

  2. Pancreatic cancer

    Time frame: 1997-2010

  3. Stomach cancer

    Time frame: 1997-2010

  4. Cataract

    Time frame: 1997-2010

  5. LUTS (Lower urinary tract symptom)

    Time frame: 1997-2010

  6. Cardiovascular Diseases

    Time frame: 1997-2010

  7. Mortality

    Time frame: 1997-2010

  8. Colorectal Cancer

    Time frame: 1997-2010

  9. Bladder cancer

    Time frame: 1997-2010

  10. Fractures, hip fractures

    Time frame: 1997-2014

Sponsors and collaborators

Lead sponsor

Karolinska Institutet

Other

Registry information

Acronym: COSM

Important dates

Study start
1997
Primary completion
1997
First posted
May 21, 2010
Registry last updated
Feb 28, 2014

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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