Skip to main content
OpenTrials
Completed

NCT Number: NCT05906966

Cognitive, Emotional, Communicative, and Motor Development in Children Born From IOC

The study focuses on children born after in vitro fertilization (IVF) of cryopreserved oocytes.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

ART Child Development

Sex eligibility

All sexes

Study type

Observational

Primary location

Istituto Clinico Humanitas

Rozzano, Milano, 20089, Italy

About this study

  • Evaluate whether the cognitive development of children born by IVF of cryopreserved oocytes is comparable to expected peer development.
  • Evaluate whether the emotional development of children born by IVF of cryopreserved oocytes is comparable to expected peer development.
  • Evaluate whether the communicative development of children born by IVF of cryopreserved oocytes is comparable to expected peer development.
  • Evaluate whether the motor development of children born by IVF of cryopreserved oocytes is comparable to expected peer development

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Live births from pregnancies resulted from fresh and frozen embryo transfer after fertilization of cryopreserved oocytes are included.

Exclusion criteria

  • Children born from pregnancies obtained from cryopreserved donated oocytes have been excluded.

Treatment and study plan

Phone contact

Other

. All mothers of children of born from cryopreserved oocytes will be contacted by phone and administered a questionnaire, to gather additional information about further psychomotor development of children.

Primary outcomes

  1. Cognitive development

    Time frame: 18 YEARS

    Evaluation through a newly edited questionnaire according to milestones, set for age, established by CDC guidelines (Zubler et al, 2022). The objective is to compare cognitive development of children born by IVF of cryopreserved oocytes in comparison to expected peer development. Answers will be reported as yes/no according if milestones are achieved or not.

  2. Communicative development

    Time frame: 18 YEARS

    Evaluation through a newly edited questionnaire according to milestones, set for age, established by CDC guidelines (Zubler et al, 2022). The objective is to compare communicative development of children born by IVF of cryopreserved oocytes in comparison to expected peer development. Answers will be reported as yes/no according if milestones are achieved or not.

  3. Motor development

    Time frame: 18 YEARS

    Evaluation through a newly edited questionnaire according to milestones, set for age, established by CDC guidelines (Zubler et al, 2022). The objective is to compare motor development of children born by IVF of cryopreserved oocytes in comparison to expected peer development. Answers will be reported as yes/no according if milestones are achieved or not.

  4. Emotional development

    Time frame: 18 YEARS

    Evaluation through a newly edited questionnaire according to milestones, set for age, established by CDC guidelines (Zubler et al, 2022). The objective is to compare emotional development of children born by IVF of cryopreserved oocytes in comparison to expected peer development. Answers will be reported as yes/no according if milestones are achieved or not.

Sponsors and collaborators

Lead sponsor

Istituto Clinico Humanitas

Other

Registry information

Official study title

Cognitive, Emotional, Communicative, and Motor Development in Children Born From in Vitro Fertilization of Cryopreserved Oocytes

Important dates

Study start
2023
Primary completion
2023
Study completion
2023
First posted
Jun 18, 2023
Registry last updated
Jun 18, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.