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NCT Number: NCT06969911

Clinical Evaluation of CAD/CAM vs. Conventional Veneer Restorations

The aim of the study is to clinically evaluate tooth-supported veneer restorations fabricated using the CAD/CAM process in comparison to conventionally manufactured pressed veneers on anterior teeth and to assess their long-term performance. Survival and success rates of anterior veneer restorations, as well as patient satisfaction, will be evaluated.

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Key information

Conditions

Malformed Tooth Congenital Abnormalities Congenital, Hereditary, and Neonatal Diseases and Abnormalities Stomatognathic Diseases Stomatognathic System Abnormalities Tooth Abnormalities Tooth Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

About this study

Functional and aesthetic complaints caused by congenital malformations and acquired tooth damage are widely spread. Discomfort involves reduced chewing ability, phonetic problems, hypersensitivity and aesthetic impairments.

Conventionally fabricated all-ceramic veneer restorations reveal a long history of clinical success in minimally invasive rehabilitation of the anterior dentition. Nevertheless, conventional manufacturing techniques are prone to fabrication mistakes and must be handled by experienced dental technicians and dentists which results in very high fabrication costs. Therefore, access to minimally invasive restorations is currently restricted for most of the patients. Innovative CAD/CAM techniques have revolutionised restorative treatment options over the last decades and have made all-ceramic restorations more affordable for patients. With further improvements of the CAD/CAM milling devices the machinability of high-strength glass ceramic is now possible.

The aim of both treatment procedures will be to avoid any extensive additional tooth structure removal, to provide long-term survival and success of the integrated restorations and to improve patient´s satisfaction. Up to now scientific evidence on the clinical performance of CAD/CAM fabricated veneers is very limited. Aim of this trial is to evaluate if the clinical performance of anterior restorations after minimally invasive therapeutic intervention with CAD/CAM veneers compared to conventionally fabricated veneers. Functional and aesthetic treatment results will be assessed for five years and evaluated with regard to failure and succes veneer restorations as well as patient satisfaction.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients ≥ 18 years of age
  • Patients that reveal indication for a minimum of 2 and a maximum of 6 anterior veneer restorations

Exclusion criteria

  • Patients that reveal multiple missing teeth, poor oral hygiene, pronounced parafunctions or with allergies to any of the applied materials

Treatment and study plan

Laminate veneer CAD/CAM

Procedure

Minimally invasive therapeutic intervention with CAD/CAM veneers

Laminate Veneer Convetional

Procedure

Minimally invasive therapeutic intervention with CAD/CAM veneers

Primary outcomes

  1. Prosthetic survival time

    Time frame: 5 Years

    The primary objective is to compare the prosthetic survival time of the restorations (conventional vs. CAD/CAM veneers).

Secondary outcomes

  1. Prosthetic success

    Time frame: 5 Years

    The secondary objectives are to compare the prosthetic success of the restorations (conventional vs. CAD/CAM veneers), the documentation of failures such as fractures and the assessment of patient centered satisfaction.

Sponsors and collaborators

Lead sponsor

Heinrich-Heine University, Duesseldorf

Other

Registry information

Official study title

Long-term Performance and Longevity of Minimally Invasive CAD/CAM Versus Conventional Anterior Veneer Restorations: a Randomized Controlled Trial Over 5 Years.

Important dates

Study start
2025
Primary completion
2032
Study completion
2032
First posted
May 14, 2025
Registry last updated
May 14, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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