Clinical Efficacy and Safety of Metformin Versus Apple Cider Vinegar (ACV) in Prediabetics

The goal of this clinical trial is to compare efficacy and safety of metformin versus apple cider vinegar in prediabetics . The main question[s] it aims to answer are:

* Efficacy of metformin versus apple cider vinegar in prediabetics * Safety of metformin versus apple cider vinegar in prediabetics

Researchers will compare group of prediabetics taking metformin with group of prediabetics taking apple cider vinegar to see if there is difference in safety and efficacy..

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Key information

Conditions

PreDiabetes Diabetes Mellitus Endocrine System Diseases Glucose Metabolism Disorders Metabolic Diseases Nutritional and Metabolic Diseases Prediabetic State

Age range

17 year–40 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Diabetologist Clinics (02)

Karachi, Pakistan

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Males and Female
17-40 years age
Body Mass index (BMI) overweight and obese
FBS (100-125 mg/dl)
HBA1c 5.7% to 6.4%

Exclusion criteria

Concomitant medical problems as established diabetes, hepatic or renal insufficiencies etc.
Known allergy or intolerance to metformin or apple cider vinegar

Treatment and study plan

Metformin Hydrochloride (HCL)

Drug

Tab Metformin HCL 500mg twice per day aimed at improving glycemic indices in Prediabetics

apple cider vinegar

Dietary Supplement

Apple cider vinegar aimed at improving glycemic indices in Prediabetics

Primary outcomes

Glycated Hemoglobin

Time frame: 12 weeks

Change in glycosylated hemoglobin (HbA1c ) in percent
Fasting Blood Sugar

Time frame: 12 weeks

Change in fasting blood sugar (FBS) in mg/dL

Sponsors and collaborators

Lead sponsor

Bahria University

Other

Registry information

Acronym: BUHSCK

Important dates

Study start: 2023
Primary completion: 2023
Study completion: 2023
First posted: Mar 8, 2023
Registry last updated: Aug 28, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed