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Completed

NCT Number: NCT04042948

Clinical Effect of Preventive Use of Tylenol on Fever After Removal of Drainage Tube in Lumbar Fusion Surgery

This study evaluates the influence of Non-steroidal Anti-inflammatory Drugs on preventing fever after the removal of drainage tube in the patients who suffered lumbar fusion surgery, if the outcome turn out positive, the preventive use of non-steroidal anti-inflammatory drugs could decrease the possibility of fever happening when we remove the tube.

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Key information

Conditions

Lumbar Spinal Stenosis Body Temperature Changes Bone Diseases Fever Hernia Intervertebral Disc Displacement Lumbar Disc Herniation Lumbar Radiculopathy Musculoskeletal Diseases Nervous System Diseases Neuromuscular Diseases Pathological Conditions, Anatomical Pathological Conditions, Signs and Symptoms Peripheral Nervous System Diseases Radiculopathy Signs and Symptoms Spinal Diseases Spinal Stenosis

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Peking University Third Hospital

Beijing, Haidian, 110191, China

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • adult patient
  • diagnosis of lumbar spinal stenosis
  • perform decompression and fusion surgery and lay a drainage tube
  • understand the test and could sign the name

Exclusion criteria

  • beside the inclusion criteria

Treatment and study plan

Tylenol

Drug

when we decide to remove the drainage tube, we ask the patient to take a pill of tylenol, and another pill in 12h later

Primary outcomes

  1. the rate of fever after the removal of drainage tube

    Time frame: 24 hours

    we test the temperature of the patient in 24h after the removal of tube, we define fever if the temperature is higher than 37.8 degree

Secondary outcomes

  1. the level of WBC

    Time frame: 24 hours

    we compare the change of the level of WBC of two groups in 24h after the removal of the drainage tube

  2. the level of CRP

    Time frame: 24 hours

    we compare the change of the level of CRP of two groups in 24h after the removal of the drainage tube

  3. the level of ESR

    Time frame: 24 hours

    we compare the change of the level of ESR of two groups in 24h after the removal of the drainage tube

  4. the temperature

    Time frame: 24 hours

    we compare the change of the level of temperature of two groups in 24h after the removal of the drainage tube

Sponsors and collaborators

Lead sponsor

Peking University Third Hospital

Other

Registry information

Official study title

Randomized Controlled Study of Fever Probability, Risk Factors and Preventive Use of Non-steroidal Anti-inflammatory Drugs on Fever After Removal of Drainage Tube After Lumbar Fusion

Important dates

Study start
2019
Primary completion
2019
Study completion
2019
First posted
Aug 2, 2019
Registry last updated
Jun 18, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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