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NCT Number: NCT06834958

Clinical Diagnosis of Acute Appendicitis with Normal WBCS Count with Role of Inflammatory Markers and Radiology

The aim of this study is to describe the proportion of pa-tients with normal preoperative inflammatorymarkers among patients with histopathologically proven acute appendicitis

Active, Not Recruiting

This study is active but is not currently recruiting participants.

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Key information

Conditions

Acute Appendicitis Appendicitis Cecal Diseases Digestive System Diseases Gastroenteritis Gastrointestinal Diseases Infections Intestinal Diseases Intraabdominal Infections

Age range

14 day–60 day

Sex eligibility

All sexes

Study type

Observational

Primary location

Assuit university

Asyut, Egypt

About this study

2.4.1- Type of the study: prospective clinical trial study 2.4. 2- Study Setting: Assuit university hospital 2.4. 3- Study subjects:

  • Inclusion criteria:

patients complain of Rt iliac pain with Us positive for acute appendicitis with WBCS normal .

  • Exclusion criteria:

malignant mass cancer appendix mesenteric adentis cecal diverticulum salpingitis c. Sample Size Calculation: 50 cases 2.4.4 -Study tools (in detail, e.g., lab methods, instruments, steps, chemicals, …): Lab WBCS count CRP level Neutrophil differential count Clinical correlation US findings and MSCT if needed

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion

  • Male or female patients é clinically diagnosed acute appendicitis with normal WBCS

Exclusion criteria

  • complicated AA (perforation, peri appendicular abscess or suspicion of a tumor.

2_inflammatory bowel diseases 3_inability to co-operate and give informed consent 4_diffuse peritonitis 5_Patients with serious comorbid conditions DM & renal insufficiency, serum creatinine > 150 μmol/l 6_Pregnant & lactating patient 7_Patients with advanced malignancies & pt on immunosuppressive drugs

Treatment and study plan

Appendectomy

Procedure

Open surgery for appendix which is inflamed

Primary outcomes

  1. Surgery done if needed

    Time frame: Days of hospital reservation

    Patient with acute appendicitis and normal WBCS count will be under observation for while but people with evidence on imaging and high inflammatory markers will go under surgery

Sponsors and collaborators

Lead sponsor

Assiut University

Other

Registry information

Important dates

Study start
2025
Primary completion
2027
Study completion
2028
First posted
Feb 19, 2025
Registry last updated
Feb 19, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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