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Completed

NCT Number: NCT03281863

Clinical Audit on the Managment in Assiut University Children Hospital

clinical audit on the Managment of rheumatic fever in assiut university children hospital.

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Key information

Conditions

Rheumatic Fever Arthritis Bacterial Infections Bacterial Infections and Mycoses Connective Tissue Diseases Gram-Positive Bacterial Infections Infections Joint Diseases Musculoskeletal Diseases Rheumatic Diseases Skin and Connective Tissue Diseases Streptococcal Infections

Age range

5 year–15 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Egypt

Asyut, Egypt

About this study

Acute rheumatic fever,an auto immune response to Group A streptococcus infection of the upper respiratory tract,may result in carditis.when the inflammation leads to permenant damage of the valves the individual has rheumatic heart disease.

Recurrences of rheumatic fever are likely in the absence of preventive measures and may cause further cardiac valve and muscle damage,leading to heart failure,stroke and premature death.bacterial endocarditis is also a complication.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • patients with confirmed diagnosis of rheumatic fever based on laboratory investigations.

Exclusion criteria

  • No

Treatment and study plan

C reactive protein, anti streptolysin o antibody test ,erythrocyte sedimentation rate

Diagnostic Test

Throat culture to detect the causative organism

Other names: Throat culture

Primary outcomes

  1. laboratory investigations (ASOt , ESR . CRP)

    Time frame: One year from October 2017 to september 2018

    laboratory investigations that measure the inflammation process will be used and the target that the ASOt not increase 1/400

Secondary outcomes

  1. clinical measures

    Time frame: One year from October 2017 to september 2018

    improvement of arthritis if found

Sponsors and collaborators

Lead sponsor

Assiut University

Other

Registry information

Official study title

Clinical Audit on the Managment of Rheumatic Fever in Assiut University Children Hospital

Important dates

Study start
2018
Primary completion
2020
Study completion
2020
First posted
Sep 13, 2017
Registry last updated
Mar 26, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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